1-(2-Aminophenyl)pyrrole

CAS NO.：6025-60-1
Empirical Formula: C10H10N2
Molecular Weight: 158.2
MDL number: MFCD00005344
EINECS: 227-884-2
SAFETY DATA SHEET (SDS)
Update Date: 2026-09-12 18:55:06

What is 1-(2-Aminophenyl)pyrrole?

Chemical properties

LIGHT BEIGE TO BROWN CRYSTAL. POWDER AND NEEDLES

The Uses of 1-(2-Aminophenyl)pyrrole

1-(2-Aminophenyl)pyrrole is used in the synthesis of 4-substituted pyrrolo[1,2-a]quinoxaline derivatives. It participates in Pt(IV)-catalyzed hydroamination triggered cyclization reaction to yield fused pyrrolo [1,2-a] quinoxalines. It is also used as primary and secondary intermediates. They act as antileishmanial agents.

The Uses of 1-(2-Aminophenyl)pyrrole

1-(2-Aminophenyl)pyrrole was used in the synthesis of 4-substituted pyrrolo[1,2-a]quinoxaline derivatives.

General Description

1-(2-Aminophenyl)pyrrole participates in Pt(IV)-catalyzed hydroamination triggered cyclization reaction to yield fused pyrrolo [1,2-a] quinoxalines. It reacts with aromatic or heteroaromatic aldehydes in ethanol and catalytic amounts of acetic acid to yield 4,5-dihydropyrrolo[1,2-a]quinoxalines. Thin films of poly(1-(2-aminophenyl)pyrrole) has been prepared via oxidative electropolymerization.

Properties of 1-(2-Aminophenyl)pyrrole

Melting point:	96-98 °C(lit.)
Boiling point:	273.29°C (rough estimate)
Density	1.1192 (rough estimate)
refractive index	1.6392 (estimate)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
pka	2.09±0.10(Predicted)
Water Solubility	Insoluble in water.
BRN	1307631
CAS DataBase Reference	6025-60-1(CAS DataBase Reference)

Safety information for 1-(2-Aminophenyl)pyrrole

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.