(-)-Corey lactone 4-phenylbenzoate alcohol
Synonym(s):(3aα,4α,5β,6aα)-(−)-Hexahydro-4-(hydroxymethyl)-2-oxo-2H-cyclopenta[b]furan-5-yl 1,1′-biphenyl-4-carboxylate;(3aR,4S,5R,6aS)-Hexahydro-4-hydroxymethyl-5-(4-phenylbenzoyloxy)cyclopenta[b]furan-2-one
- CAS NO.：31752-99-5
- Empirical Formula: C21H20O5
- Molecular Weight: 352.38
- MDL number: MFCD00078077
- EINECS: 608-667-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:12:55
What is (-)-Corey lactone 4-phenylbenzoate alcohol?
Chemical properties
Off-White to Pale Yellow Solid
The Uses of (-)-Corey lactone 4-phenylbenzoate alcohol
(-) Corey lactone phenylbenzoate is a key intermediate in the synthesis of prostaglandins. Versatile building block for prostaglandins. Building block for a potent and selective antiglaucoma agent analog of PGF2α.
Properties of (-)-Corey lactone 4-phenylbenzoate alcohol
| Melting point: | 131-132 °C(lit.) |
| Boiling point: | 446°C (rough estimate) |
| alpha | -89 º (c=1, CHCl3) |
| Density | 1.1818 (rough estimate) |
| refractive index | 1.5400 (estimate) |
| storage temp. | 2-8°C |
| solubility | Chloroform, Ethyl Acetate |
| form | Solid |
| pka | 14.79±0.10(Predicted) |
| color | Off-White to Pale Yellow |
| optical activity | [α]20/D 87°, c = 1 in chloroform |
| Water Solubility | insoluble |
| BRN | 1294692 |
| CAS DataBase Reference | 31752-99-5(CAS DataBase Reference) |
Safety information for (-)-Corey lactone 4-phenylbenzoate alcohol
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for (-)-Corey lactone 4-phenylbenzoate alcohol
| InChIKey | SZJVIFMPKWMGSX-UHFFFAOYSA-N |
New Products
2-(3-Methyl-1,2,4-oxadiazol-5-yl)acetic acid (as potassium salt) 2-fluoro-4-iodoaniline 4-Iodo-3,5-dimethylbenzonitrile Atorvastatin amide impurity/Atorvastatin EP Impurity F(Calcium Salt) Lantanoprost rc B Clidinium Bromide Impurity Noradrenaline EP Impurity D/Noradrenaline Methyl Ether Cetirizine EP Impurity A/Cetirizine CBHP Impurity N-Nitroso hydroxy Cetrizine EP Impurity-A (4-Fluoro-2-methoxy-5-nitro- phenyl)-[4- (1-methyl-1H- indol-3- yl)-pyrimidin-2-yl]- amine 6-bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole tert-butyl 4-(6-((7-cyclo pentyl -6-(dimethyl carbamoyl) -7H-pyrrolo [2,3-d]pyrimidin-2-yl) amino)pyridin-3-yl) piperazine-1-carboxylate 2-Fluoro-4-nitrotoluene 1-(2-amino-5-hydroxy phenyl)propan-1-one (3R,4R)-1-benzyl-N,4-dimethylpiperidin-3- amine 3-(Dimethylamino)benzoic acid 2-Amino-5-chloropyridine 4-(Methylamino)-3-nitrobenzoic Acid 5-Chloro-2-Nitroaniline 3,5-dibenzyloxy Acetophenone 2,4-Diamino-6-hydroxypyrimidine 2-Chloro Benzylcyanide 3-chlorobenzyl cyanide 3,4 Diethoxy BenzylcyanideRelated products of tetrahydrofuran
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