(+/-)-CGP-12177 HYDROCHLORIDE
- CAS NO.：81047-99-6
- Empirical Formula: C14H21N3O3
- Molecular Weight: 279.33
- MDL number: MFCD00069230
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-04-23 13:52:06
What is (+/-)-CGP-12177 HYDROCHLORIDE?
The Uses of (+/-)-CGP-12177 HYDROCHLORIDE
CGP 12177 Hydrochloride is a selective β3-adrenoceptor agonist.
What are the applications of Application
CGP 12177 hydrochloride is a β1/β2-AR adrenoreceptor agonist
Definition
ChEBI: A benzimidazole that is benzimidazol-2-one substituted at position 4 by a 3-(tert-butylamino)-2-hydroxypropoxy group.
Biological Activity
Partial agonist at β 3 -adrenoceptors. β 1 - and β 2 -adrenoceptor antagonist (K i values are 0.9, 4 and 88 nM for β 1 , β 2 and β 3 receptors respectively).
Properties of (+/-)-CGP-12177 HYDROCHLORIDE
| Melting point: | >256°C (dec.) |
| Boiling point: | 376.3±37.0 °C(Predicted) |
| Density | 1.179 |
| storage temp. | Store at RT |
| solubility | DMSO: >10 mg/mL |
| form | solid |
| pka | 11.48±0.30(Predicted) |
| color | white |
Safety information for (+/-)-CGP-12177 HYDROCHLORIDE
Computed Descriptors for (+/-)-CGP-12177 HYDROCHLORIDE
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