α-Bromocinnamaldehyde

Chemical properties

light yellow to ochre crystalline powder

The Uses of α-Bromocinnamaldehyde

α-Bromocinnamaldehyde was used in the synthesis of 3,4-diaryl 1H-pyrazoles. It was also used in the preparation of spiro imidazolidine-oxazolidine intermediate via guanidinium ylide mediated aziridination.

General Description

α-Bromocinnamaldehyde is commonly employed as an anti-mildew agent in commercial products.

Hazard

Causes somnolence in oral, intraperitoneal, and subcutaneous lethal-dose studies of rats; A skin and strong eye irritant; Toxic by ingestion;

Synthesis

The synthesis of α-Bromocinnamaldehyde is as follows:
The cinnamaldehyde and glacial acetic acid were stirred and bromine was added after cooling. Then add anhydrous potassium carbonate, reactants heated reflux for half an hour, cooling, precipitation coarse product. The crude product is dissolved by ethanol and recrystallized to obtain the finished product with a yield of about 80%.