(+)-Biotin-PEG8-NHS Ester
- CAS NO.：2143968-03-8
- Empirical Formula: C33H56N4O14S
- Molecular Weight: 764.88
- MDL number: MFCD27977502
- Update Date: 2026-05-28 05:38:03
What is (+)-Biotin-PEG8-NHS Ester?
Biological Activity
Biotin-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Properties of (+)-Biotin-PEG8-NHS Ester
| Density | 1.29±0.1 g/cm3(Predicted) |
| pka | 13.90±0.40(Predicted) |
Safety information for (+)-Biotin-PEG8-NHS Ester
Computed Descriptors for (+)-Biotin-PEG8-NHS Ester
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