(-)-BETA-HYDRASTINE
Synonym(s):(1R,9S)-(−)-β-Hydrastine
- CAS NO.：118-08-1
- Empirical Formula: C21H21NO6
- Molecular Weight: 383.39
- MDL number: MFCD00152561
- EINECS: 204-233-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-02-02 18:10:39
What is (-)-BETA-HYDRASTINE?
Description
(1R,9S)-(–)-β-Hydrastine is an enantiomer of the alkaloid hydrastine that inhibits dopamine biosynthesis (IC50 = 20.7 μM in PC12 cells) by inhibiting tyrosine hydroxylase activity. It inhibits dopamine release with an IC50 value of 66.5 μM in the presence of high extracellular K+ levels. It also inhibits L-type and caffeine-activated store-operated Ca2+ channels and prevents Ca2+ leakage from intracellular stores.
The Uses of (-)-BETA-HYDRASTINE
anesthetic (local), antiarrhythmic
The Uses of (-)-BETA-HYDRASTINE
(-)-β-Hydrastine is an inhibitor of Dopamine biosynthesis.
What are the applications of Application
(1R,9S)-(–)-β-Hydrastine is an inhibitor of Dopamine biosynthesis
Definition
ChEBI: A natural product found in Hydrastis canadensis.
Properties of (-)-BETA-HYDRASTINE
| Melting point: | 132℃ |
| Boiling point: | 510.32°C (rough estimate) |
| alpha | D20 -50° (c = 0.3 in abs alc) |
| Density | 1.339±0.06 g/cm3 (20 ºC 760 Torr) |
| refractive index | 1.5614 (estimate) |
| storage temp. | −20°C |
| solubility | DMF: 10 mg/ml; DMSO: 10 mg/ml |
| form | A crystalline solid |
| pka | 7.8(at 25℃) |
| color | White to light yellow |
| Water Solubility | 30mg/L(20 ºC) |
| CAS DataBase Reference | 118-08-1(CAS DataBase Reference) |
Safety information for (-)-BETA-HYDRASTINE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral |
Computed Descriptors for (-)-BETA-HYDRASTINE
New Products
Mirtazapine Impurity C/Mirtazapine Lactam Impurity N,O-Dimethylhydroxylamine hydrochloride Tetrabutylammonium perchlorate N,N CARBONYL DIIMIDAZOLE 2-Amino-5-bromo-4-(trifluoromethyl)pyridine（RM for Indian lab) (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid (R)-1-Benzyl-3-pyrrolidinecarbonitrile N-Nitroso hydroxy Cetrizine EP Impurity-A Noradrenaline EP Impurity D/Noradrenaline Methyl Ether Cetirizine EP Impurity A/Cetirizine CBHP Impurity Lantanoprost rc B Clidinium Bromide Impurity 2,2'-(5-methyl-1,3-phenylene)-di(2-Methylpropionitrile) 1-methyl amino-2,4-dinitro benzene 5-Methyl-1,3-benzenediacetonitrile 4-Fluorothiophenol (R)-BoroLeu-(+)-Pinanediol-CF3COOH 4-(5-amino-1-methyl-1h-benzoimidazol-2-yl)-butyric acid isopropyl ester. 3,4 Diethoxy Benzylcyanide 2-Chloro Benzylcyanide 3-chlorobenzyl cyanide 3,4 Dimethoxy Benzylcyanide valeronitrile 4-Bromo BenzylcyanideRelated products of tetrahydrofuran
![2-[2-(Methylamino)benzoyl]-3,4-dihydro-β-carboline-1(2H)-one](https://img.chemicalbook.in/CAS/20150408/GIF/526-43-2.gif)
You may like
-
Hydrastine CAS 118-08-1View Details
118-08-1 -
Bendamustine deschloroethyl acid ethyl ester 2517968-40-8 NLT 95%View Details
2517968-40-8 -
Acebutolol EP Impurity K NLT 95%View Details
74143-33-2 -
Clidinium Bromide Impurity NLT 95%View Details
.6581-06-2 -
192110-67-2 NLT 95%View Details
192110-67-2 -
Cetirizine EP Impurity A/Cetirizine CBHP Impurity NLT 95%View Details
59872-62-1 -
.2005-04-1 N-Nitroso hydroxy Cetrizine EP Impurity-A NLT 95%View Details
.2005-04-1 -
145773-22-1 Lantanoprost rc B NLT 95%View Details
145773-22-1
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.