(+/-)AMETHOPTERIN
- CAS NO.：60388-53-6
- Empirical Formula: C20H22N8O5
- Molecular Weight: 454.44
- MDL number: MFCD00064369
- EINECS: 262-213-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-05 11:31:08
What is (+/-)AMETHOPTERIN?
Chemical properties
yellow to orange crystalline powder
The Uses of (+/-)AMETHOPTERIN
(+/-)Amethopterin is a folic acid antagonist and anticancer agent.
The Uses of (+/-)AMETHOPTERIN
Amethopterin is an antineoplastic, antirheumatic, folic acid antagonist
The Uses of (+/-)AMETHOPTERIN
Racemic Methotrexate (M260675), a folic acid antagonist. Used as a antineoplastic and antirheumatic.
What are the applications of Application
(±)Amethopterin is a folic acid and aminopterin derivative, folic acid antagonist, and anticancer agent.
Definition
ChEBI: 2-[[[4-[(2,4-diamino-6-pteridinyl)methyl-methylamino]phenyl]-oxomethyl]amino]pentanedioic acid is a member of folic acids.
Properties of (+/-)AMETHOPTERIN
| Melting point: | 195 °C (dec.)(lit.) |
| Density | 1.536±0.06 g/cm3(Predicted) |
| storage temp. | −20°C |
| solubility | H2O: Add a minimal amount of 0.1 L NaOH to solubilize, then dilute in neutral buffer or saline. Diluted stock is stable for 1week refrigerated and for 1month frozen at?20°C. |
| form | powder |
| pka | 3.47±0.10(Predicted) |
| color | yellow |
Safety information for (+/-)AMETHOPTERIN
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for (+/-)AMETHOPTERIN
New Products
4-Iodo-3,5-dimethylbenzonitrile 2-fluoro-4-iodoaniline 2-(3-Methyl-1,2,4-oxadiazol-5-yl)acetic acid (as potassium salt) 6,6'-methylenebis(9-methyl-3-((2-methyl-1H-imidazol-1-yl)methyl)-2,3-dihydro-1H-carbazol-4(9H)-one) 3-Bromo-2-fluorobenzoic acid Quinuclidine-4-carbonitrile N,N CARBONYL DIIMIDAZOLE 2-Amino-5-bromo-4-(trifluoromethyl)pyridine（RM for Indian lab) (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid Tetrabutylammonium perchlorate N,O-Dimethylhydroxylamine hydrochloride (R)-1-Benzyl-3-pyrrolidinecarbonitrile Bupropian related compound F Lantanoprost rc B Clidinium Bromide Impurity Noradrenaline EP Impurity D/Noradrenaline Methyl Ether Cetirizine EP Impurity A/Cetirizine CBHP Impurity N-Nitroso hydroxy Cetrizine EP Impurity-A 4-(5-amino-1-methyl-1h-benzoimidazol-2-yl)-butyric acid isopropyl ester. 1,4-bis(methylsulfonyl)butane 4-Cyano-N-Methacryloyl-3-Trifluoromethyl Aniline 5-Methyl-1,3-benzenediacetonitrile 4-Fluorothiophenol 1-methyl amino-2,4-dinitro benzeneRelated products of tetrahydrofuran
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