(+/-)AMETHOPTERIN
- CAS NO.：60388-53-6
- Empirical Formula: C20H22N8O5
- Molecular Weight: 454.44
- MDL number: MFCD00064369
- EINECS: 262-213-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 03:22:36
What is (+/-)AMETHOPTERIN?
Chemical properties
yellow to orange crystalline powder
The Uses of (+/-)AMETHOPTERIN
(+/-)Amethopterin is a folic acid antagonist and anticancer agent.
The Uses of (+/-)AMETHOPTERIN
Amethopterin is an antineoplastic, antirheumatic, folic acid antagonist
The Uses of (+/-)AMETHOPTERIN
Racemic Methotrexate (M260675), a folic acid antagonist. Used as a antineoplastic and antirheumatic.
What are the applications of Application
(±)Amethopterin is a folic acid and aminopterin derivative, folic acid antagonist, and anticancer agent.
Definition
ChEBI: 2-[[[4-[(2,4-diamino-6-pteridinyl)methyl-methylamino]phenyl]-oxomethyl]amino]pentanedioic acid is a member of folic acids.
Properties of (+/-)AMETHOPTERIN
| Melting point: | 195 °C (dec.)(lit.) |
| Density | 1.536±0.06 g/cm3(Predicted) |
| storage temp. | −20°C |
| solubility | H2O: Add a minimal amount of 0.1 L NaOH to solubilize, then dilute in neutral buffer or saline. Diluted stock is stable for 1week refrigerated and for 1month frozen at?20°C. |
| form | powder |
| pka | 3.47±0.10(Predicted) |
| color | yellow |
Safety information for (+/-)AMETHOPTERIN
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for (+/-)AMETHOPTERIN
New Products
3-AMINO-3-(2-FLUORO-PHENYL)-PROPIONIC ACID Pentadecanoic acid Hendecanoic acid 2-AMINO-3-METHYLQUINOLINE HYDROCHLORIDE 3-Hydroxypropionitrile DL-3-Amino-3-(2-methoxyphenyl)propionic acid 5-Bromo-2-Fluoropyridine 2,3-Diamino-5-Chloropyridine 2-Amino-3-Hydroxypyridine 2,6-Diamino Pyridine 4-Amino-2-Chloropyridine 2-Hydroxy-4-Picoline 4-(4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile 4-Bromo-3-(ethoxymethyl)benzoic acid 2,4-Dichloro-5-methoxyaniline 4,6-Dichloro-2-(propylthio)pyrimidin-5-amine N2-Isobutyryl-2'-O-methylguanosine 2-chloro-5-methylpyridin-4-amine 4-Bromobenzaldehyde 2-Chloro-6-nitro benzothiazole 2-Amino-4-phenyl-thiazole 4-Chloro-2-methyl quinoline 2-(Chloromethyl) quinazolin-4(3H)-one 5-Phenyl-[1,3,4]-thiadiazol-2-amineRelated products of tetrahydrofuran
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