(+/-)AMETHOPTERIN
- CAS NO.：60388-53-6
- Empirical Formula: C20H22N8O5
- Molecular Weight: 454.44
- MDL number: MFCD00064369
- EINECS: 262-213-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-07-16 07:06:08
What is (+/-)AMETHOPTERIN?
Chemical properties
yellow to orange crystalline powder
The Uses of (+/-)AMETHOPTERIN
(+/-)Amethopterin is a folic acid antagonist and anticancer agent.
The Uses of (+/-)AMETHOPTERIN
Amethopterin is an antineoplastic, antirheumatic, folic acid antagonist
The Uses of (+/-)AMETHOPTERIN
Racemic Methotrexate (M260675), a folic acid antagonist. Used as a antineoplastic and antirheumatic.
What are the applications of Application
(±)Amethopterin is a folic acid and aminopterin derivative, folic acid antagonist, and anticancer agent.
Definition
ChEBI: 2-[[[4-[(2,4-diamino-6-pteridinyl)methyl-methylamino]phenyl]-oxomethyl]amino]pentanedioic acid is a member of folic acids.
Properties of (+/-)AMETHOPTERIN
| Melting point: | 195 °C (dec.)(lit.) |
| Density | 1.536±0.06 g/cm3(Predicted) |
| storage temp. | −20°C |
| solubility | H2O: Add a minimal amount of 0.1 L NaOH to solubilize, then dilute in neutral buffer or saline. Diluted stock is stable for 1week refrigerated and for 1month frozen at?20°C. |
| form | powder |
| pka | 3.47±0.10(Predicted) |
| color | yellow |
Safety information for (+/-)AMETHOPTERIN
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for (+/-)AMETHOPTERIN
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9-Mesityl-10-methylacridinium perchlorate Sulfapyridine Fmoc-OSu (R)-(-)-2-Amino-1-propanol Cyclobutanone 5-bromo-4-fluoro-2-nitrobenzaldehyde 4 pentyn 1 ol N-Vinylformamide Phenethyl cinnamate Pyrrolo[1,2-a]pyrimidine-6-carboxylic acid, 4,6,7,8-tetrahydro-4-oxo-, sodium salt (1:1), (6S) Ethyl 3-phenylpropanoate β-Bromostyrene Methacrylate-PEG-Methacrylate, Mn:35000 2,4-Dihydroxyacetophenone 2-Chloro 5-Fluoro Pyridine Vasicinone 2-Chloroisonicotinic Acid Tween 80 or Polysorbate 80 5-Bromo-1-Pentyne 1-(2-Methyl-5-nitrophenyl)guanidine Nitrate Methyl trans-4-Aminocyclohexanecarboxylate Hydrochloride N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamide 4-Nitrobenzotrifluoride 2-Pentyn-1-oLRelated products of tetrahydrofuran
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