(+/-)-alpha-Lipoamide
- CAS NO.：940-69-2
- Empirical Formula: C8H15NOS2
- Molecular Weight: 205.34
- MDL number: MFCD00005475
- EINECS: 213-375-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 06:06:27
What is (+/-)-alpha-Lipoamide?
The Uses of (+/-)-alpha-Lipoamide
(±)-α-Lipoamide may be used in treatment of insulin resistance by stimulating mitochondrial biogenesis. When used in combination with Alprostadil, it has shown to have a good therapeutic effect on early diabetic nephropathy.
Definition
ChEBI: A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of lipoic acid with ammonia.
Storage
Store at -20°C
Purification Methods
DL--Lipoamide is recrystallised from EtOH and has UV with max 331nm in MeOH. [Reed et al. J Biol Chem 232 143 1958, IR: Wagner et al. J Am Chem Soc 78 5079 1956, Beilstein 19/7 V 238.]
Properties of (+/-)-alpha-Lipoamide
| Melting point: | 127-129 °C(lit.) |
| Boiling point: | 399.2±11.0 °C(Predicted) |
| Density | 1.1989 (rough estimate) |
| refractive index | 1.5364 (estimate) |
| storage temp. | Sealed in dry,2-8°C |
| solubility | Dichloromethane (Slightly), DMSO (Slightly, Heated, Sonicated), Ethanol (Slightl |
| form | Solid |
| pka | 16.59±0.40(Predicted) |
| color | Pale Yellow to Yellow |
| CAS DataBase Reference | 940-69-2(CAS DataBase Reference) |
Safety information for (+/-)-alpha-Lipoamide
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P501:Dispose of contents/container to..… |
Computed Descriptors for (+/-)-alpha-Lipoamide
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