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Home Product name list(+/-)12-HETE

(+/-)12-HETE

CAS NO.：71030-37-0
Empirical Formula: C20H32O3
Molecular Weight: 320.47
MDL number: MFCD00065826
SAFETY DATA SHEET (SDS)
Update Date: 2026-07-17 09:03:53

(+/-)12-HETE Structural

What is (+/-)12-HETE?

Description

(±)12-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid. The biological activity of (±)12-HETE is similar to that of its constituent enantiomers (Item Nos. 34560 and 34570). It aggregates neutrophils with an EC₅₀ value of 40 nM.

What are the applications of Application

(±)12-HETE is an aggregator of neutrophils

Definition

ChEBI: (5Z,8Z,10E,14Z)-12-hydroxyicosatetraenoic acid is the (5Z,8Z,10E,14Z)-stereoisomer of 12-HETE. It has a role as a mouse metabolite. It is a conjugate acid of a 12-HETE(1-).

Properties of (+/-)12-HETE

Boiling point:	487.7±45.0 °C(Predicted)
Density	0.984±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS (pH 7.2): 0.8 mg/ml
form	Liquid
pka	4.75±0.10(Predicted)
color	Colorless to light yellow

Safety information for (+/-)12-HETE

Computed Descriptors for (+/-)12-HETE

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(+/-)12-HPETE

12(S)-HPETE

12(S)-HPETE [1-14C]

12(S)-HPETE [1-14C]

12(R)-HETE

12(S)-HETE-[5,6,8,9,11,12,14,15-3H(N)]-

12(S)-HETE-[5,6,8,9,11,12,14,15-3H(N)]-

12(S),20-DIHETE

12(S),20-DIHETE

(s)-12-hete

(+/-)12-HETE

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