(+)-1,2-BIS((2S,5S)-2,5-DIPHENYLPHOSPHOLANO)ETHANE

Synonym(s):(S,S)-Ph-BPE,BPE

CAS NO.：824395-67-7
Empirical Formula: C34H36P2
Molecular Weight: 506.61
MDL number: MFCD07369028
SAFETY DATA SHEET (SDS)
Update Date: 2025-07-29 21:08:05

(+)-1,2-BIS((2S,5S)-2,5-DIPHENYLPHOSPHOLANO)ETHANE Structural

What is (+)-1,2-BIS((2S,5S)-2,5-DIPHENYLPHOSPHOLANO)ETHANE?

The Uses of (+)-1,2-BIS((2S,5S)-2,5-DIPHENYLPHOSPHOLANO)ETHANE

(+)-1,2-Bis((2S,5S)-2,5-diphenylphospholano)ethane is a chiral reagent that is used as a catalyst and also as an enantioselective reagent in synthetic chemistry.

The Uses of (+)-1,2-BIS((2S,5S)-2,5-DIPHENYLPHOSPHOLANO)ETHANE

It is a DuPhos and BPE ligands which are highly efficient privileged ligands. It is a chiral phosphine ligand used in the asymmetric hydrogenation of allylic sulfoxides.

What are the applications of Application

(+)-1,2-Bis((2S,5S)-2,5-diphenylphospholano)ethane is a potentially useful synthetic intermediate

General Description

Chiral Phosphine ligand used in the asymmetric hydrogenation of allylic sulfoxides

Dynamic Kinetic Resolution of Allylic Sulfoxides by Rh-Catalyzed Hydrogenation: A Combined Theoretical and Experimental Mechanistic Study

Properties of (+)-1,2-BIS((2S,5S)-2,5-DIPHENYLPHOSPHOLANO)ETHANE

Melting point:	143-147 °C
Boiling point:	654.2±55.0 °C(Predicted)
alpha	+182.7° (c 1.0, CH2Cl2)
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
solubility	Sparingly Soluble (3.2E-5 g/L) (25°C).
form	solid
color	white
Sensitive	Air Sensitive
CAS DataBase Reference	824395-67-7

Safety information for (+)-1,2-BIS((2S,5S)-2,5-DIPHENYLPHOSPHOLANO)ETHANE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.