CHEMICAL AND PHYSICAL PROPERTIES
| Color/Form | White to off-white powder |
|---|---|
| Solubility | Lipophilic and poorly soluble in water at neutral pH. Solubility increases at more acidic pH. |
| LogP | 4.7 |
| Stability/Shelf Life | Stable under recommended storage conditions. /Rotigotine hydrochloride/ |
| Optical Rotation | White crystalline solid. Specific optical rotation: -55.79 deg at 25 °C/578 °C (c = 0.99 in methanol) /Rotigotine hydrochloride/ |
| Other Experimental Properties | Non-hygroscopic. Sensitive to oxidation |
COMPUTED DESCRIPTORS
| Molecular Weight | 315.5 g/mol |
|---|---|
| XLogP3 | 4.9 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 6 |
| Exact Mass | 315.16568559 g/mol |
| Monoisotopic Mass | 315.16568559 g/mol |
| Topological Polar Surface Area | 51.7 Ų |
| Heavy Atom Count | 22 |
| Formal Charge | 0 |
| Complexity | 337 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 1 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Rotigotine is a member of tetralins.