CHEMICAL AND PHYSICAL PROPERTIES
| Physical Description | Solid |
|---|---|
| Boiling Point | 410.5±45.0 °C at 760 mmHg |
| Melting Point | 243-250 °C |
| Solubility | 133 mg/mL |
| LogP | 3.06 |
| LogS | -2.9 |
| Stability/Shelf Life | Stable under recommended storage conditions. /Ropinirole hydrochloride/ |
| Dissociation Constants | 10.17 |
| Collision Cross Section | 163.8 Ų [M+H]+ [CCS Type: TW, Method: Major Mix IMS/Tof Calibration Kit (Waters)] |
| Other Experimental Properties | Crystals from acetonitrile, mp 241-243 °C. Solublility in water: 133 mg/mL /Ropinirole hydrochloride/ |
COMPUTED DESCRIPTORS
| Molecular Weight | 260.37 g/mol |
|---|---|
| XLogP3 | 2.7 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 7 |
| Exact Mass | 260.188863393 g/mol |
| Monoisotopic Mass | 260.188863393 g/mol |
| Topological Polar Surface Area | 32.3 Ų |
| Heavy Atom Count | 19 |
| Formal Charge | 0 |
| Complexity | 287 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Ropinirole is a member of indolones and a tertiary amine. It has a role as a dopamine agonist, an antiparkinson drug, a central nervous system drug and an antidyskinesia agent.