CHEMICAL AND PHYSICAL PROPERTIES
| Color/Form | White, crystalline powder |
|---|---|
| Odor | Oily, slightly ammoniac |
| Boiling Point | 136 °C at 1.00E+00 mm Hg |
| Melting Point | 46.5 °C |
| Solubility | Soluble in ethanol |
| LogP | 4.69 |
| Stability/Shelf Life | Stable under recommended storage conditions. /Phencyclidine hydrochloride/ |
| Decomposition | When heated to decomposition it emits toxic fumes of /nitrogen oxides/. |
| Caco2 Permeability | -4.61 |
| Dissociation Constants | 8.29 |
| Kovats Retention Index | 1918 1879 1860 1890 1880 1906.3 1887.8 1860 1870 1879 1860 1904 1890 1890 |
| Other Experimental Properties | Phencyclidine belongs to a unique family of chemicals called cyclohexylamines. |
SAFETY INFORMATION
| Signal word | Danger |
|---|---|
| Pictogram(s) |
 Flame Flammables GHS02  Skull and Crossbones Acute Toxicity GHS06  Health Hazard GHS08 |
| GHS Hazard Statements |
H225:Flammable liquids H370:Specific target organ toxicity, single exposure |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P311:Call a POISON CENTER or doctor/physician. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. |
COMPUTED DESCRIPTORS
| Molecular Weight | 243.4 g/mol |
|---|---|
| XLogP3 | 3.6 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 1 |
| Rotatable Bond Count | 2 |
| Exact Mass | 243.198699802 g/mol |
| Monoisotopic Mass | 243.198699802 g/mol |
| Topological Polar Surface Area | 3.2 Ų |
| Heavy Atom Count | 18 |
| Formal Charge | 0 |
| Complexity | 242 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Phencyclidine is a member of the class of piperidines that is piperidine in which the nitrogen is substituted with a 1-phenylcyclohexyl group. Formerly used as an anaesthetic agent, it exhibits both hallucinogenic and neurotoxic effects. It has a role as a neurotoxin, a psychotropic drug, an anaesthetic and a NMDA receptor antagonist. It is a member of piperidines and a member of benzenes. It derives from a hydride of a piperidine.