CHEMICAL AND PHYSICAL PROPERTIES
| Physical Description | Solid |
|---|---|
| Color/Form | Dark brown viscous oil |
| Boiling Point | 268-274 °C at 5.00E-01 mm Hg |
| Melting Point | 224-226 (Salt) |
| Solubility | 31.1 mg/L (at 37 °C) |
| LogP | 4.36 |
| LogS | -4.15 |
| Stability/Shelf Life | Light sensitive. /Fluphenazine Decanoate/ |
| Decomposition | When heated to decomposition it emits very toxic fumes of /hydrogen fluoride/, /nitroge and sulfur/ oxides. |
| Dissociation Constants | 7.9 |
| Collision Cross Section | 198.1 Ų [M+H]+ [CCS Type: DT, Method: single field calibrated] |
| Kovats Retention Index | 3045 3032 3015 3025 3045 3045 3045 3045 3050 3050 3050 3050 3050 3050 3050 3060 3060 3060 3060 3045 3056 3035 3085 3015.8 3065 3019.9 |
| Other Experimental Properties | Pale yellow to yellow-orange viscous liquid or oily solid /Fluphenazine enanthate/ |
SAFETY INFORMATION
| Signal word | Danger |
|---|---|
| Pictogram(s) |
 Flame Flammables GHS02  Skull and Crossbones Acute Toxicity GHS06  Health Hazard GHS08 |
| GHS Hazard Statements |
H225:Flammable liquids H301:Acute toxicity,oral H370:Specific target organ toxicity, single exposure |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P260:Do not breathe dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P280:Wear protective gloves/protective clothing/eye protection/face protection. P311:Call a POISON CENTER or doctor/physician. P321:Specific treatment (see … on this label). P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P405:Store locked up. |
COMPUTED DESCRIPTORS
| Molecular Weight | 437.5 g/mol |
|---|---|
| XLogP3 | 4.4 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 8 |
| Rotatable Bond Count | 6 |
| Exact Mass | 437.17486812 g/mol |
| Monoisotopic Mass | 437.17486812 g/mol |
| Topological Polar Surface Area | 55.2 Ų |
| Heavy Atom Count | 30 |
| Formal Charge | 0 |
| Complexity | 544 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Fluphenazine is a member of the class of phenothiazines that is 10H-phenothiazine having a trifluoromethyl subsitituent at the 2-position and a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at the N-10 position. It has a role as a phenothiazine antipsychotic drug, a dopaminergic antagonist and an anticoronaviral agent. It is an organofluorine compound, a member of phenothiazines and a N-alkylpiperazine. It derives from a hydride of a 10H-phenothiazine.