COMPUTED DESCRIPTORS
| Molecular Weight | 109.13 g/mol |
|---|---|
| XLogP3 | 0.3 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 0 |
| Exact Mass | 109.063997236 g/mol |
| Monoisotopic Mass | 109.063997236 g/mol |
| Topological Polar Surface Area | 29.8 Ų |
| Heavy Atom Count | 8 |
| Formal Charge | 0 |
| Complexity | 93.7 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Imidazole-Pyrazole is a synthetic agent, also known as IMPY, with antineoplastic properties. IMPY inhibits ribonucleotide reductase, an enzyme that converts ribonucleotides to deoxyribonucleotides during DNA synthesis; this agent specifically binds the smaller, nonheme-iron subunit of the enzyme. (NCI04)