67-45-8

Product Name: Furazolidone

Formula: C8H7N3O5

Synonyms: 3-(5-Nitrofurfurylideneamino)-2-oxazolidinone;Furazolidone

Inquiry

CHEMICAL AND PHYSICAL PROPERTIES SAFETY INFORMATION COMPUTED DESCRIPTORS PRODUCT INTRODUCTION RELATED SUPPLIERS

CHEMICAL AND PHYSICAL PROPERTIES

Physical Description	Yellow odorless solid; [Merck Index]
Color/Form	Yellow crystals from DMF (N,N-dimethylformamide)
Odor	Odorless
Melting Point	254-256
Solubility	40 mg/L (at 25 °C)
Vapor Pressure	0.0000026 [mmHg]
LogP	-0.04
Decomposition	When heated to decomposition it emits toxic fumes of /nitrogen oxides/.
Collision Cross Section	146.88 Å² [M+H]+ 146 Å² [M+Na]+
Other Experimental Properties	Decomposed by alkali
Chemical Classes	Other Uses -> Animal Feed Additives

SAFETY INFORMATION

Signal word	Warning
Pictogram(s)	Health Hazard GHS08
GHS Hazard Statements	H361:Reproductive toxicity
Precautionary Statement Codes	P280:Wear protective gloves/protective clothing/eye protection/face protection.

COMPUTED DESCRIPTORS

Molecular Weight	225.16 g/mol
XLogP3	-0.1
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	2
Exact Mass	225.03857033 g/mol
Monoisotopic Mass	225.03857033 g/mol
Topological Polar Surface Area	101 Å²
Heavy Atom Count	16
Formal Charge	0
Complexity	326
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	1
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

PRODUCT INTRODUCTION

description

Furazolidone is a member of the class of oxazolidines that is 1,3-oxazolidin-2-one in which the hydrogen attached to the nitrogen is replaced by an N-{[(5-nitro-2-furyl)methylene]amino} group. It has antibacterial and antiprotozoal properties, and is used in the treatment of giardiasis and cholera. It has a role as an EC 1.4.3.4 (monoamine oxidase) inhibitor, an antitrichomonal drug, an antiinfective agent and an antibacterial drug. It is a member of oxazolidines and a nitrofuran antibiotic.