CHEMICAL AND PHYSICAL PROPERTIES
| Color/Form | Crystals (from diethyl ether) |
|---|---|
| Melting Point | 208 °C |
| Solubility | ODORLESS; WHITE OR PRACTICALLY WHITE, CRYSTALLINE POWDER; INSOL IN CHLOROFORM & ETHER; SOL IN DIL ALKALI HYDROXIDE /NALORPHINE HYDROCHLORIDE/ |
| LogP | log Kow = 1.86 |
| Optical Rotation | Specific optical rotation: -155.3 °C (c = 3 in methanol) |
| Decomposition | When heated to decomposition it emits very toxic fumes of /nitrogen oxides/. |
| Dissociation Constants | pKa = 7.64 |
| Other Experimental Properties | Decomp at 258-259 °C; crystals from alc; soluble in water /Nalorphine hydrobromide/ |
COMPUTED DESCRIPTORS
| Molecular Weight | 311.4 g/mol |
|---|---|
| XLogP3 | 1.9 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 2 |
| Exact Mass | 311.15214353 g/mol |
| Monoisotopic Mass | 311.15214353 g/mol |
| Topological Polar Surface Area | 52.9 Ų |
| Heavy Atom Count | 23 |
| Formal Charge | 0 |
| Complexity | 549 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 5 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Nalorphine is a morphinane alkaloid.