61-32-5
Product Name:
methicillin
Formula:
C17H20N2O6S
Synonyms:
2,6-Dimethoxyphenyl-penicillin;Methicillin;Methicillin Selective Supplement;Staphcillin
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
| Physical Description | Solid |
|---|---|
| Solubility | FINE, WHITE, CRYSTALLINE POWDER; FREELY SOL IN METHANOL, PYRIDINE; SLIGHTLY SOL IN PROPYL AND AMYL ALCOHOL, ETHYLENE CHLORIDE; INSOL IN BENZENE; ODORLESS OR HAVING SLIGHT ODOR /METHICILLIN SODIUM/ |
| LogP | 1.22 |
| Stability/Shelf Life | SALT IS STABLE IN DRY FORM; UNSTABLE IN ACIDIC MEDIA & LOSES POTENCY DISSOLVED IN 0.85% SODIUM CHLORIDE OR IN DEXTROSE SOLN. /METHICILLIN SODIUM/ |
| Dissociation Constants | 2.77 |
SAFETY INFORMATION
| Signal word | Warning |
|---|---|
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral |
COMPUTED DESCRIPTORS
| Molecular Weight | 380.4 g/mol |
|---|---|
| XLogP3 | 1.2 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 7 |
| Rotatable Bond Count | 5 |
| Exact Mass | 380.10420754 g/mol |
| Monoisotopic Mass | 380.10420754 g/mol |
| Topological Polar Surface Area | 131 Ų |
| Heavy Atom Count | 26 |
| Formal Charge | 0 |
| Complexity | 600 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 3 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Methicillin is a penicillin that is 6-aminopenicillanic acid in which one of the amino hydrogens is replaced by a 2,6-dimethoxybenzoyl group. It has a role as an antibacterial drug. It is a penicillin and a penicillin allergen. It is a conjugate acid of a methicillin(1-).