57-68-1
Product Name:
2-(4-Aminobenzenesulfonamido)-4,6-dimethylpyrimidine
Formula:
C12H14N4O2S
Synonyms:
4,6-Dimethylsulfadiazine;4-Amino-N-(4,6-dimethyl-2-pyrimidinyl)benzenesulfonamide;Sulfadimethyldiazine;Sulfadimidine;Sulfamethazine
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
| Physical Description | Sulfamethazine appears as odorless sticky, white or creamy-white crystalline powder. Slightly bitter taste. An antibacterial. |
|---|---|
| Color/Form | Crystals from dioxane-water |
| Odor | Odorless |
| Taste | Slightly bitter taste |
| Melting Point | 387 to 392 °F (NTP, 1992) |
| Solubility | less than 1 mg/mL at 68.9 °F (NTP, 1992) |
| Density | 1.4655 g/cu cm |
| LogP | 0.89 |
| Stability/Shelf Life | Stable under recommended storage conditions. |
| Dissociation Constants | 7.59 |
| Collision Cross Section | 161.7 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards] |
| Kovats Retention Index | 2613 |
| Other Experimental Properties | log Kow = 0.25 at pH 7 |
COMPUTED DESCRIPTORS
| Molecular Weight | 278.33 g/mol |
|---|---|
| XLogP3 | 0.3 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 3 |
| Exact Mass | 278.08374688 g/mol |
| Monoisotopic Mass | 278.08374688 g/mol |
| Topological Polar Surface Area | 106 Ų |
| Heavy Atom Count | 19 |
| Formal Charge | 0 |
| Complexity | 377 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Sulfamethazine appears as odorless sticky, white or creamy-white crystalline powder. Slightly bitter taste. An antibacterial.