127-69-5
Product Name:
Sulfisoxazole
Formula:
C11H13N3O3S
Synonyms:
N1-(3,4-Dimethyl-5-isoxazolyl)sulfanilamide;4-Amino-N-(3,4-dimethyl-5-isoxazolyl)benzenesulfonamide;Sulfafurazole;Sulfisoxazole
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
| Physical Description | Sulfisoxazole is an odorless white to yellowish crystalline powder. Slightly bitter taste. Acid to litmus. (NTP, 1992) |
|---|---|
| Color/Form | Colorless prisms |
| Odor | Odorless |
| Taste | Bitter |
| Melting Point | 383 to 388 °F (NTP, 1992) |
| Solubility | >40.1 [ug/mL] (The mean of the results at pH 7.4) |
| LogP | 1.01 |
| LogS | -2.91 |
| Stability/Shelf Life | IN AIR SENSITIVE TO LIGHT; UNSTABLE IN ALKALINE SOLN |
| Decomposition | When heated to decomposition it emits very toxic fumes of sulfoxides and nitroxides. |
| pH | ACID TO LITMUS |
| Dissociation Constants | 5 |
| Collision Cross Section | 159.1 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards] |
| Other Experimental Properties | Mol wt: 309.34. Should not be confused with N4-acetyl sulfisoxazole which is a metabolite. Tasteless crystals; mp 193-194 °C. Sol (mg/mL): 0.07 in water; 4.93 in methanol; 5.7 in 95% ethanol; 0.94 in ether; 29.0 in chloroform /Acetyl sulfisoxazole/ |
SAFETY INFORMATION
| Signal word | Warning |
|---|---|
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
COMPUTED DESCRIPTORS
| Molecular Weight | 267.31 g/mol |
|---|---|
| XLogP3 | 1 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 3 |
| Exact Mass | 267.06776246 g/mol |
| Monoisotopic Mass | 267.06776246 g/mol |
| Topological Polar Surface Area | 107 Ų |
| Heavy Atom Count | 18 |
| Formal Charge | 0 |
| Complexity | 374 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Sulfisoxazole is an odorless white to yellowish crystalline powder. Slightly bitter taste. Acid to litmus. (NTP, 1992)