57-57-8
Product Name:
2-Oxetanone
Formula:
C3H4O2
Synonyms:
3-Hydroxypropionic acid lactone;Hydracrylic acid β-lactone;Oxetan-2-one
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
| Physical Description | Beta-propiolactone appears as a colorless liquid with a slightly sweetish, pungent odor. Used as an intermediate in organic synthesis; disinfectant, sterilant for blood plasma, tissue grafts, vaccines, enzymes and surgical instruments. (EPA, 1998) |
|---|---|
| Color/Form | A COLORLESS LIQUID |
| Odor | PUNGENT |
| Boiling Point | 324 °F at 760 mmHg decomposes (EPA, 1998) |
| Melting Point | -27 °F (EPA, 1998) |
| Flash Point | 158 °F (EPA, 1998) |
| Solubility | 10 to 50 mg/mL at 66 °F (NTP, 1992) |
| Density | 1.146 at 68 °F (EPA, 1998) - Denser than water; will sink |
| Vapor Density | 2.5 (NTP, 1992) - Heavier than air; will sink (Relative to Air) |
| Vapor Pressure | 3.4 mmHg at 77 °F (EPA, 1998) |
| LogP | -0.564 |
| Stability/Shelf Life | STABLE WHEN STORED AT +5 °C IN GLASS CONTAINERS |
| Decomposition | 162 °C |
| Polymerization | TENDS TO POLYMERIZE ON STORAGE |
| Refractive Index | INDEX OF REFRACTION: 1.413 @ 20 °C/D; 1.4110 @ 25 °C |
| Other Experimental Properties | VERY HIGH CHEMICAL REACTIVITY DUE TO PRESENCE OF STRAINED FOUR-MEMBERED LACTONE RING |
| Chemical Classes | Other Classes -> Lactones |
SAFETY INFORMATION
| Signal word | Danger |
|---|---|
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06  Health Hazard GHS08 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H330:Acute toxicity,inhalation H350:Carcinogenicity |
| Precautionary Statement Codes |
P202:Do not handle until all safety precautions have been read and understood. P260:Do not breathe dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
COMPUTED DESCRIPTORS
| Molecular Weight | 72.06 g/mol |
|---|---|
| XLogP3 | -0.2 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 0 |
| Exact Mass | 72.021129366 g/mol |
| Monoisotopic Mass | 72.021129366 g/mol |
| Topological Polar Surface Area | 26.3 Ų |
| Heavy Atom Count | 5 |
| Formal Charge | 0 |
| Complexity | 57.9 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Beta-propiolactone appears as a colorless liquid with a slightly sweetish, pungent odor. Used as an intermediate in organic synthesis; disinfectant, sterilant for blood plasma, tissue grafts, vaccines, enzymes and surgical instruments. (EPA, 1998)