CHEMICAL AND PHYSICAL PROPERTIES
| Physical Description | Solid |
|---|---|
| Melting Point | 276-281 |
| Solubility | Very soluble |
| LogP | 0.8 |
| Other Experimental Properties | CRYSTALS FROM DIL ETHANOL; MP 276-281 °C (DECOMP) /SULFATE/ |
COMPUTED DESCRIPTORS
| Molecular Weight | 198.31 g/mol |
|---|---|
| XLogP3 | 0.5 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 3 |
| Exact Mass | 198.18444672 g/mol |
| Monoisotopic Mass | 198.18444672 g/mol |
| Topological Polar Surface Area | 67.6 Ų |
| Heavy Atom Count | 14 |
| Formal Charge | 0 |
| Complexity | 167 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Guanethidine is a member of the class of guanidines in which one of the hydrogens of the amino group has been replaced by a 2-azocan-1-ylethyl group. It has a role as an antihypertensive agent, an adrenergic antagonist and a sympatholytic agent. It is a member of guanidines and a member of azocanes. It is functionally related to a guanidine. It derives from a hydride of an azocane.