50-91-9
Product Name:
Floxuridine
Formula:
C9H11FN2O5
Synonyms:
floxuridine;FUDR;5-Fluoro-2′-deoxyuridine;FdUrd, FUdR, 5-FdU, Floxuridine;2′-Deoxy-5-fluorouridine
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
| Physical Description | Inhibits DNA synthesis. (NTP, 1992) |
|---|---|
| Color/Form | Crystals from butyl acetate |
| Odor | ODORLESS |
| Melting Point | 302 to 304 °F (NTP, 1992) |
| Solubility | 11900 mg/L |
| LogP | -1.16 |
| Optical Rotation | Crystals from butyl acetate, mp 150-151 °C. Specific optical rotation at 25 °C for D (sodium) line = -21 deg (c = 2 in water) /alpha-Anomer/ |
| Decomposition | When heated to decomposition it emits very toxic fumes of /hydrogen fluoride and nitrogen oxides/. |
| Dissociation Constants | 7.44 |
SAFETY INFORMATION
| Signal word | Danger |
|---|---|
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06 |
| GHS Hazard Statements |
H301:Acute toxicity,oral |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P405:Store locked up. P501:Dispose of contents/container to..… |
COMPUTED DESCRIPTORS
| Molecular Weight | 246.19 g/mol |
|---|---|
| XLogP3 | -1.2 |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 2 |
| Exact Mass | 246.06519962 g/mol |
| Monoisotopic Mass | 246.06519962 g/mol |
| Heavy Atom Count | 17 |
| Formal Charge | 0 |
| Complexity | 386 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 3 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Inhibits DNA synthesis. (NTP, 1992)