465-21-4
Product Name:
Bufalin
Formula:
C24H34O4
Synonyms:
3β,14-Dihydroxy-5β,20(22)-bufadienolide;5β, 20(22)-Bufadienolide-3β, 14-diol;5β,20(22)-Bufadienolide-3β,14-diol;Bufalin - CAS 465-21-4 - Calbiochem
Inquiry
SAFETY INFORMATION
| Signal word | Danger |
|---|---|
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06 |
| GHS Hazard Statements |
H300:Acute toxicity,oral |
COMPUTED DESCRIPTORS
| Molecular Weight | 386.5 g/mol |
|---|---|
| XLogP3 | 3.2 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 1 |
| Exact Mass | 386.24570956 g/mol |
| Monoisotopic Mass | 386.24570956 g/mol |
| Topological Polar Surface Area | 66.8 Ų |
| Heavy Atom Count | 28 |
| Formal Charge | 0 |
| Complexity | 741 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 8 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Bufalin is a 14beta-hydroxy steroid that is bufan-20,22-dienolide having hydroxy substituents at the 5beta- and 14beta-positions. It has been isolated from the skin of the toad Bufo bufo. It has a role as an antineoplastic agent, a cardiotonic drug, an anti-inflammatory agent and an animal metabolite. It is a 3beta-hydroxy steroid and a 14beta-hydroxy steroid. It is functionally related to a bufanolide.