23583-48-4
Product Name:
8-BROMOADENOSINE 3':5'-CYCLIC MONOPHOSPHATE
Formula:
C10H11BrN5O6P
Synonyms:
8-Br-A-3:5-MP;8-Br-cAMP;8-Bromo-cAMP
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COMPUTED DESCRIPTORS
| Molecular Weight | 408.10 g/mol |
|---|---|
| XLogP3 | -1.5 |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 10 |
| Rotatable Bond Count | 1 |
| Exact Mass | 406.96303 g/mol |
| Monoisotopic Mass | 406.96303 g/mol |
| Topological Polar Surface Area | 155 Ų |
| Heavy Atom Count | 23 |
| Formal Charge | 0 |
| Complexity | 532 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 4 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
8-Br-cAMP is a 3',5'-cyclic purine nucleotide that is 3',5'-cyclic AMP bearing an additional bromo substituent at position 8 on the adenine ring. An activator of cyclic AMP-dependent protein kinase, but resistant to degradation by cyclic AMP phosphodiesterase. It has a role as a protein kinase agonist and an antidepressant. It is a 3',5'-cyclic purine nucleotide, an organobromine compound and an adenyl ribonucleotide. It is functionally related to a 3',5'-cyclic AMP.