CHEMICAL AND PHYSICAL PROPERTIES
| Color/Form | CRYSTALS FROM PETROLEUM ETHER |
|---|---|
| Melting Point | 75-76ºC |
| Solubility | 3.32 mg/L at 25ºC |
| LogP | 4.11 |
| Stability/Shelf Life | PERMITS MORE STABLE LIQ & TABLET DOSAGE FORMS /NAPSYLATE/ |
| Optical Rotation | SPECIFIC OPTICAL ROTATION: -68.2 DEG @ 25 °C/D (CHLOROFORM, 0.6%) |
| Kovats Retention Index | 2185 2185 |
| Other Experimental Properties | ESSENTIALLY ODORLESS & HAS BITTER TASTE; MELTS WITHIN RANGE OF 4 DEG BETWEEN 158 & 165 °C /NAPSYLATE/ |
COMPUTED DESCRIPTORS
| Molecular Weight | 339.5 g/mol |
|---|---|
| XLogP3 | 4.2 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 9 |
| Exact Mass | 339.219829168 g/mol |
| Monoisotopic Mass | 339.219829168 g/mol |
| Topological Polar Surface Area | 29.5 Ų |
| Heavy Atom Count | 25 |
| Formal Charge | 0 |
| Complexity | 397 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 2 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Levopropoxyphene is a 1-benzyl-3-(dimethylamino)-2-methyl-1-phenylpropyl propanoate. It has a role as an antitussive. It is an enantiomer of a dextropropoxyphene.