CHEMICAL AND PHYSICAL PROPERTIES
| Isoelectric Point | 4.9 |
|---|---|
| Other Experimental Properties | Clear, colorless solution /Victoza/ |
SAFETY INFORMATION
| Signal word | Warning |
|---|---|
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
COMPUTED DESCRIPTORS
| Molecular Weight | 3751 g/mol |
|---|---|
| XLogP3 | -3.4 |
| Hydrogen Bond Donor Count | 54 |
| Hydrogen Bond Acceptor Count | 55 |
| Rotatable Bond Count | 132 |
| Exact Mass | 3749.9498161 g/mol |
| Monoisotopic Mass | 3748.9464612 g/mol |
| Topological Polar Surface Area | 1510 Ų |
| Heavy Atom Count | 266 |
| Formal Charge | 0 |
| Complexity | 8760 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 31 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Liraglutide is a lipopeptide that is an analogue of human GLP-1 in which the lysine residue at position 27 is replaced by arginine and a hexadecanoyl group attached to the remaining lysine via a glutamic acid spacer. Used as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. It has a role as a glucagon-like peptide-1 receptor agonist and a neuroprotective agent. It is a lipopeptide and a polypeptide.