2016-88-8
Product Name:
Amiloride hydrochloride
Formula:
C6H8ClN7O.ClH
Synonyms:
N-Amidino-3,5-diamino-6-chloropyrazinecarboxamide hydrochloride dihydrate;Acid-Sensing Ion Channel Modulator I, ASIC Channel Modulator I;Amiloride hydrochloride dihydrate;Amiloride, Hydrochloride - CAS 2016-88-8 - Calbiochem;N-Amidino-3,5-diamino-6-chloropyrazinecarboxamide hydrochloride hydrate
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
| Physical Description | Amiloride hydrochloride appears as crystalline solid or very light yellow powder. (NTP, 1992) |
|---|---|
| Melting Point | 560.3 °F (NTP, 1992) |
| Solubility | less than 1 mg/mL at 67.1 °F (NTP, 1992) |
| Collision Cross Section | 145.7 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards] |
SAFETY INFORMATION
| Signal word | Danger |
|---|---|
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06 |
| GHS Hazard Statements |
H301:Acute toxicity,oral |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P405:Store locked up. P501:Dispose of contents/container to..… |
COMPUTED DESCRIPTORS
| Molecular Weight | 266.09 g/mol |
|---|---|
| Hydrogen Bond Donor Count | 5 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 1 |
| Exact Mass | 265.0245633 g/mol |
| Monoisotopic Mass | 265.0245633 g/mol |
| Topological Polar Surface Area | 159 Ų |
| Heavy Atom Count | 16 |
| Formal Charge | 0 |
| Complexity | 279 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 2 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Amiloride hydrochloride appears as crystalline solid or very light yellow powder. (NTP, 1992)