174671-46-6
Product Name:
Tavaborole
Formula:
C7H6BFO2
Synonyms:
1,3-Dihydro-5-fluoro-1-hydroxy-2,1-benzoxaborole;5-Fluoro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole;AN2690;AN-2690
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
| Color/Form | White to off-white powder |
|---|---|
| Solubility | Slightly soluble in water |
COMPUTED DESCRIPTORS
| Molecular Weight | 151.93 g/mol |
|---|---|
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 0 |
| Exact Mass | 152.0444878 g/mol |
| Monoisotopic Mass | 152.0444878 g/mol |
| Topological Polar Surface Area | 29.5 Ų |
| Heavy Atom Count | 11 |
| Formal Charge | 0 |
| Complexity | 155 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Tavaborole is a member of the class of benzoxaboroles that is 1,3-dihydro-1-hydroxy-2,1-benzoxaborole substituted at position 5 by a fluoro group. A topical antifungal agent used for the treatment of onychomycosis (fungal infection of the toenails and fingernails). It has a role as an antifungal agent, a protein synthesis inhibitor and an EC 6.1.1.4 (leucine--tRNA ligase) inhibitor. It is an organofluorine compound and a benzoxaborole.