CHEMICAL AND PHYSICAL PROPERTIES
| Solubility | Mol wt, 1213.41. Hygroscopic white to off-white powder. Freely sol in water, methanol; slightly sol in ethanol /Acetate/ |
|---|
COMPUTED DESCRIPTORS
| Molecular Weight | 1093.3 g/mol |
|---|---|
| XLogP3 | 0.3 |
| Hydrogen Bond Donor Count | 16 |
| Hydrogen Bond Acceptor Count | 18 |
| Rotatable Bond Count | 23 |
| Exact Mass | 1092.64306214 g/mol |
| Monoisotopic Mass | 1092.64306214 g/mol |
| Topological Polar Surface Area | 412 Ų |
| Heavy Atom Count | 77 |
| Formal Charge | 0 |
| Complexity | 1900 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 14 |
| Undefined Atom Stereocenter Count | 2 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Caspofungin is an antimycotic echinocandin lipopeptide, semisynthetically derived from a fermentation product of the fungus Glarea lozoyensis. Caspofungin inhibits 1,3-beta-glucan synthase, resulting in decreased synthesis of beta(1,3)-D-glucan (an essential component of the fungal cell wall), weakening of the fungal cell wall, and fungal cell wall rupture. This agent is active against Aspergillus and Candida species.