162635-04-3
Product Name:
Temsirolimus
Formula:
C56H87NO16
Synonyms:
42-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate]-rapamycin;CCI-779
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
| Physical Description | Solid |
|---|---|
| Color/Form | White to off-white powder |
| Solubility | Practically insoluble in water; soluble in alcohol |
| Dissociation Constants | No ionizable functional groups |
| Other Experimental Properties | Non-hygroscopic |
SAFETY INFORMATION
| Signal word | Danger |
|---|---|
| Pictogram(s) |
 Health Hazard GHS08 |
| GHS Hazard Statements |
H360:Reproductive toxicity H413:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P201:Obtain special instructions before use. P202:Do not handle until all safety precautions have been read and understood. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P308+P313:IF exposed or concerned: Get medical advice/attention. P405:Store locked up. |
COMPUTED DESCRIPTORS
| Molecular Weight | 1030.3 g/mol |
|---|---|
| XLogP3 | 5.6 |
| Hydrogen Bond Donor Count | 4 |
| Hydrogen Bond Acceptor Count | 16 |
| Rotatable Bond Count | 11 |
| Exact Mass | 1029.60248569 g/mol |
| Monoisotopic Mass | 1029.60248569 g/mol |
| Topological Polar Surface Area | 242 Ų |
| Heavy Atom Count | 73 |
| Formal Charge | 0 |
| Complexity | 2010 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 15 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 4 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Temsirolimus is a Kinase Inhibitor. The mechanism of action of temsirolimus is as a Protein Kinase Inhibitor.