CHEMICAL AND PHYSICAL PROPERTIES
| Color/Form | Crystals from methanol |
|---|---|
| Odor | Odorless |
| Taste | Tasteless |
| Melting Point | 178-179 °C |
| Solubility | insoluble in water |
| Stability/Shelf Life | DECOMP SLOWLY IN LIGHT; RELATIVELY STABLE IN HEAT. /PAMOATE/ |
| Collision Cross Section | 143 Ų [M+H]+ [CCS Type: TW] |
COMPUTED DESCRIPTORS
| Molecular Weight | 206.31 g/mol |
|---|---|
| XLogP3 | 1.6 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 2 |
| Exact Mass | 206.08776963 g/mol |
| Monoisotopic Mass | 206.08776963 g/mol |
| Topological Polar Surface Area | 43.8 Ų |
| Heavy Atom Count | 14 |
| Formal Charge | 0 |
| Complexity | 248 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 1 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Pyrantel is a carboxamidine that is 1,4,5,6-tetrahydropyrimidine that is substituted at position 1 by a methyl group and at position 2 by an (E)-2-(2-thienyl)vinyl group. It is used, particularly as the embonate [4,4'-methylenebis(3-hydroxy-2-naphthoate)] salt, as an anthelmintic that is effective against intestinal nematodes including threadworms, roundworms and hookworms, and is included in the WHO 'Model List of Essential Medicines'. It has a role as an antinematodal drug. It is a member of thiophenes, a carboxamidine and a member of 1,4,5,6-tetrahydropyrimidines.