154-93-8
Product Name:
Carmustine
Formula:
C5H9Cl2N3O2
Synonyms:
1,3-Bis(2-chloroethyl)-1-nitrosourea;BCNU
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
| Physical Description | 1,3-bis(2-chloroethyl)-1-nitrosourea is an orange-yellow solid. (NTP, 1992) |
|---|---|
| Color/Form | Light yellow powder |
| Melting Point | 86 to 90 °F (NTP, 1992) |
| Solubility | less than 1 mg/mL at 64 °F (NTP, 1992) |
| LogP | 1.53 |
| Decomposition | When heated to decomposition, it emits very toxic fumes of /chlorine/ and /nitrogen oxides/. |
| Other Experimental Properties | Polifeprosan 20 with carmustine implant ... off-white to pale yellow wafer /Gliadel wafer/ |
SAFETY INFORMATION
| Signal word | Danger |
|---|---|
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06  Health Hazard GHS08 |
| GHS Hazard Statements |
H300:Acute toxicity,oral H350:Carcinogenicity H360:Reproductive toxicity |
| Precautionary Statement Codes |
P201:Obtain special instructions before use. P280:Wear protective gloves/protective clothing/eye protection/face protection. P308+P313:IF exposed or concerned: Get medical advice/attention. |
COMPUTED DESCRIPTORS
| Molecular Weight | 214.05 g/mol |
|---|---|
| XLogP3 | 1.5 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 4 |
| Exact Mass | 213.0071819 g/mol |
| Monoisotopic Mass | 213.0071819 g/mol |
| Topological Polar Surface Area | 61.8 Ų |
| Heavy Atom Count | 12 |
| Formal Charge | 0 |
| Complexity | 156 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
1,3-bis(2-chloroethyl)-1-nitrosourea is an orange-yellow solid. (NTP, 1992)