CHEMICAL AND PHYSICAL PROPERTIES
| Physical Description | Solid |
|---|---|
| Color/Form | Crystals form alcohol and water |
| Odor | Odorless or has slight odor. |
| Taste | TASTELESS |
| Melting Point | 225 °C |
| Solubility | 11.2 mg/L |
| LogP | 1.42 |
| Stability/Shelf Life | Commercially available methyclothiazide tablets have an expiration date of 5 yr following the date of manufacture. |
| Decomposition | When heated to decomposition it emits very toxic fumes of sulfoxides, nitroxides, and /hydrogen chloride/. |
| Dissociation Constants | 9.4 |
| Other Experimental Properties | Chars slightly below 220 °C and decomposes at 220 °C |
COMPUTED DESCRIPTORS
| Molecular Weight | 360.2 g/mol |
|---|---|
| XLogP3 | 1.4 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 7 |
| Rotatable Bond Count | 2 |
| Exact Mass | 358.9568036 g/mol |
| Monoisotopic Mass | 358.9568036 g/mol |
| Topological Polar Surface Area | 126 Ų |
| Heavy Atom Count | 20 |
| Formal Charge | 0 |
| Complexity | 571 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 1 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Methyclothiazide is a benzothiadiazine.