123714-50-1
Product Name:
Ac-Asp-Pro-Met-Ser-Ser-Thr-Tyr-Ile-Glu-Glu-Leu-Gly-Lys-Arg-Glu-Val-Thr-Ile-Pro-Pro-Lys-Tyr-Arg-Glu-Leu-Leu-Ala-NH2
Formula:
C142H230N36O44S
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COMPUTED DESCRIPTORS
| Molecular Weight | 3177.6 g/mol |
|---|---|
| XLogP3 | -9.4 |
| Hydrogen Bond Donor Count | 44 |
| Hydrogen Bond Acceptor Count | 49 |
| Rotatable Bond Count | 105 |
| Exact Mass | 3176.6620907 g/mol |
| Monoisotopic Mass | 3175.6587359 g/mol |
| Topological Polar Surface Area | 1310 Ų |
| Heavy Atom Count | 223 |
| Formal Charge | 0 |
| Complexity | 7290 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 30 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Calpastatin peptide Ac 184-210 is a 27-membered polypeptide comprising the sequence Ac-Asp-Pro-Met-Ser-Ser-Thr-Tyr-Ile-Glu-Glu-Leu-Gly-Lys-Arg-Glu-Val-Thr-Ile-Pro-Pro-Lys-Tyr-Arg-Glu-Leu-Leu-Ala-NH2. An acetylated synthetic peptide from human calpastatin that strongly inhibits both calpains I and II but not papain (a cysteine protease) or trypsin (a serine protease). It has a role as an EC 3.4.22.52 (calpain-1) inhibitor and an EC 3.4.22.53 (calpain-2) inhibitor.