CHEMICAL AND PHYSICAL PROPERTIES
| Physical Description | Bleomycin appears as colorless or yellowish powder. Possible bluish color depending on copper content. (NTP, 1992) |
|---|---|
| Color/Form | Colorless to yellow powder |
| Melting Point | 71 °C |
| Solubility | Soluble (NTP, 1992) |
| Stability/Shelf Life | In vitro, bleomycin is inactivated by agents containing sulfhydryl groups, hydrogen peroxide, and ascorbic acid. Bleomycin sulfate sterile powder is stable under refrigeration at 2-8 °C and should not be used after the expiration date is reached. |
| Other Experimental Properties | Max absorption: 244-248, 289-294 nm (e = 121-148, 102-121.5, 1%, 1 cm) /Bleomycins/ |
COMPUTED DESCRIPTORS
| Molecular Weight | 1415.6 g/mol |
|---|---|
| XLogP3 | -7.5 |
| Hydrogen Bond Donor Count | 20 |
| Hydrogen Bond Acceptor Count | 31 |
| Rotatable Bond Count | 36 |
| Exact Mass | 1414.51898128 g/mol |
| Monoisotopic Mass | 1414.51898128 g/mol |
| Topological Polar Surface Area | 685 Ų |
| Heavy Atom Count | 96 |
| Formal Charge | 1 |
| Complexity | 2580 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 9 |
| Undefined Atom Stereocenter Count | 10 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Bleomycin appears as colorless or yellowish powder. Possible bluish color depending on copper content. (NTP, 1992)