2-methylpropan-2-ol SDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
- Product name： 2-methylpropan-2-ol
- CAS： 75-65-0
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses： For R&D use only. Not for medicinal, household or other use.
- Uses advised against： none
Company Identification
- Company：Chemicalbook.in
- Address：5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
- Telephone：+91 9550333722
SECTION 2: Hazards identification
Classification of the substance or mixture
Flammable liquids, Category 2
Eye irritation, Category 2
Acute toxicity - Category 4, Inhalation
Specific target organ toxicity – single exposure, Category 3
GHS label elements, including precautionary statements
-
Pictogram(s)
- Signal word Danger
H225 Highly flammable liquid and vapour
H319 Causes serious eye irritation
H332 Harmful if inhaled
H335 May cause respiratory irritation
P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P233 Keep container tightly closed.
P240 Ground and bond container and receiving equipment.
P241 Use explosion-proof [electrical/ventilating/lighting/...] equipment.
P242 Use non-sparking tools.
P243 Take action to prevent static discharges.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P264 Wash ... thoroughly after handling.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P303+P361+P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse affected areas with water [or shower].
P370+P378 In case of fire: Use ... to extinguish.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P317 Get medical help.
P319 Get medical help if you feel unwell.
P403+P235 Store in a well-ventilated place. Keep cool.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
Substance
- Chemical name: 2-methylpropan-2-ol
- Common names and synonyms: 2-methylpropan-2-ol
- CAS number: 75-65-0
- EC number: 200-889-7
- Concentration: 100%
SECTION 4: First aid measures
Description of necessary first-aid measures
Fresh air, rest. Refer for medical attention.
Remove contaminated clothes. Rinse skin with plenty of water or shower.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Rinse mouth. Give one or two glasses of water to drink. Do NOT induce vomiting. Refer for medical attention .
Most important symptoms/effects, acute and delayed
Vapor is narcotic in action and irritating to respiratory passages. Liquid is irritating to skin and eyes. (USCG, 1999)
Indication of immediate medical attention and special treatment needed, if necessary
Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand-valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR as necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. Higher alcohols (>3 carbons) and related compounds
SECTION 5: Firefighting measures
Suitable extinguishing media
Flash back possible over considerable distance.
Specific hazards arising from the chemical
This chemical is flammable. (NTP, 1992)
Special protective actions for fire-fighters
Use water spray, alcohol-resistant foam, powder, carbon dioxide. In case of fire: keep drums, etc., cool by spraying with water.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Remove all ignition sources. Evacuate danger area! Consult an expert! Personal protection: self-contained breathing apparatus. Ventilation. Collect leaking liquid in sealable containers. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. Wash away remainder with plenty of water.
Environmental precautions
Remove all ignition sources. Evacuate danger area! Consult an expert! Personal protection: self-contained breathing apparatus. Ventilation. Collect leaking liquid in sealable containers. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. Wash away remainder with plenty of water.
Methods and materials for containment and cleaning up
Personal precautions: Use personal protective equipment. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Remove all sources of ignition. Evacuate personnel to safe areas. Beware of vapors accumulating to form explosive concentrations. Vapors can accumulate in low areas. Environmental precautions: Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Methods and materials for containment and cleaning up: Contain spillage, and then collect with an electrically protected vacuum cleaner or by wet-brushing and place in container for disposal according to local regulations.
SECTION 7: Handling and storage
Precautions for safe handling
NO open flames, NO sparks and NO smoking. Closed system, ventilation, explosion-proof electrical equipment and lighting. Do NOT use compressed air for filling, discharging, or handling. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Fireproof. Separated from strong oxidants and strong acids.Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.
SECTION 8: Exposure controls/personal protection
Control parameters
TLV: 100 ppm as TWA; A4 (not classifiable as a human carcinogen).MAK: 62 mg/m3, 20 ppm; peak limitation category: II(4); pregnancy risk group: C
no data available
Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures, such as personal protective equipment (PPE)
Wear safety goggles.
Protective gloves.
Use ventilation, local exhaust or breathing protection.
no data available
SECTION 9: Physical and chemical properties and safety characteristics
-
Physical state：
Liquid.
-
Colour：
Off-white solid block or clear colourless liquid, depending on temperature.
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Odour：
Camphor-like odor
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Melting point/freezing point：
25.7 °C. Atm. press.:101.3 kPa. Remarks:STP conditions assumed.
-
Boiling point or initial boiling point and boiling range：
82.41 °C. Atm. press.:101.3 kPa. Remarks:STP conditions assumed.
-
Flammability：
Combustible Solid Class IB Flammable Liquid: Fl.P. below 73°F and BP at or above 100°F.
-
Lower and upper explosion limit/flammability limit：
Lower flammable limit: 2.4% by volume; Upper flammable limit: 8.0% by volume
-
Flash point：
< 23 °C. Atm. press.:Preliminary test.;15 °C. Atm. press.:STP conditions assumed.
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Auto-ignition temperature：
470 °C. Atm. press.:STP conditions assumed.
-
Decomposition temperature：
no data available
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pH：
no data available
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Kinematic viscosity：
kinematic viscosity (in mm2/s) = 5.72. Temperature:25.0°C.;kinematic viscosity (in mm2/s) = 2.23. Temperature:45.0°C.
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Solubility：
Miscible with water
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Partition coefficient n-octanol/water：
Pow = 2.08. Temperature:22.5 °C.;log Pow = 0.317. Temperature:22.5 °C.
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Vapour pressure：
5 413 Pa. Temperature:25 °C.
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Density and/or relative density：
0.79. Temperature:20 °C.
-
Relative vapour density：
2.55 (vs air)
-
Particle characteristics：
no data available
SECTION 10: Stability and reactivity
Reactivity
Decomposes on contact with strong mineral acids or strong oxidants. This generates fire and explosion hazard.
Chemical stability
Heat contributes to instability
Possibility of hazardous reactions
Highly flammable liquid and vapor.The vapour mixes well with air, explosive mixtures are easily formed.Attacks plastics. [Handling Chemicals Safely 1980. p. 236]. Acetyl bromide reacts violently with alcohols or water [Merck 11th ed. 1989]. Mixtures of alcohols with concentrated sulfuric acid and strong hydrogen peroxide can cause explosions. Example: an explosion will occur if dimethylbenzylcarbinol is added to 90% hydrogen peroxide then acidified with concentrated sulfuric acid. Mixtures of ethyl alcohol with concentrated hydrogen peroxide form powerful explosives. Mixtures of hydrogen peroxide and 1-phenyl-2-methyl propyl alcohol tend to explode if acidified with 70% sulfuric acid [Chem. Eng. News 45(43):73 1967; J, Org. Chem. 28:1893 1963]. Alkyl hypochlorites are violently explosive. They are readily obtained by reacting hypochlorous acid and alcohols either in aqueous solution or mixed aqueous-carbon tetrachloride solutions. Chlorine plus alcohols would similarly yield alkyl hypochlorites. They decompose in the cold and explode on exposure to sunlight or heat. Tertiary hypochlorites are less unstable than secondary or primary hypochlorites [NFPA 491 M 1991]. Base-catalysed reactions of isocyanates with alcohols should be carried out in inert solvents. Such reactions in the absence of solvents often occur with explosive violence [Wischmeyer 1969].
Conditions to avoid
no data available
Incompatible materials
Incompatible with oxidizing materials, H2O2.
Hazardous decomposition products
Toxic gases & vapors (e.g., carbon monoxide & isobutylene) may be released in a fire involving tert-butyl alcohol.
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 - rat (male) - 3 384 mg/kg bw.
- Inhalation: LC50 - rat (male/female) - > 10 000 ppm.
- Dermal: LD50 - rabbit (male/female) - > 2 000 mg/kg bw.
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
A4; Not classifiable as a human carcinogen.
Reproductive toxicity
no data available
STOT-single exposure
The substance is irritating to the eyes. The substance may cause effects on the central nervous system. Exposure far above the OEL could cause lowering of consciousness.
STOT-repeated exposure
Repeated or prolonged contact with skin may cause dermatitis.
Aspiration hazard
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C.
SECTION 12: Ecological information
Toxicity
- Toxicity to fish: LC50 - Pimephales promelas - > 961 mg/L - 96 h.
- Toxicity to daphnia and other aquatic invertebrates: EC50 - Daphnia magna - 933 mg/L - 48 h.
- Toxicity to algae: EC50 - Pseudokirchneriella subcapitata (previous names: Raphidocelis subcapitata, Selenastrum capricornutum) - > 976 mg/L - 72 h.
- Toxicity to microorganisms: EC50 - Pseudomonas putida - > 10 g/L - 16 h.
Persistence and degradability
AEROBIC: t-Butyl alcohol, present at 100 mg/L, achieved 2.5% of its theoretical BOD in 2 weeks using an activated sludge inoculum at 30 mg/L in the Japanese MITI test(1). The biodegradation half-life of t-butyl alcohol was reported to range from about 28 to 180 days in aerobic water and 100 to 500 days in anaerobic water(2). t-Butyl alcohol reached 1% of its theoretical BOD using a sewage sludge during a 5 day incubation period(3). Using a river die-away test, t-butyl alcohol achieved 4% of its theoretical BOD in 12 days(4). t-Butyl alcohol, present at 50 mg/L, achieved 7% of its theoretical BOD in 2 weeks using an activated sludge inoculum at 30 mg/L in the Japanese MITI test(5). Approximately 96% dissolved organic carbon was removed over a 6 day incubation period using the Zahn-Wellens test, meant to simulate degradation at an industrial sewage treatment plant(5). Using an activated sludge in a prolonged closed bottle biodegradation test, t-butyl alcohol was degraded 10, 63 and 67% in 28, 42 and 56 days, respectively(6). Biodegradation of t-butyl alcohol in unamended soils collected at different depths had rates of <0.01 to 0.15 mg/L/day/gram dry soil(7).
Bioaccumulative potential
BCF values of <5 were reported for carp exposed to 6 ug/L of t-butyl alcohol during a 6 week incubation period(1). According to a classification scheme(2), this BCF suggests bioconcentration in aquatic organisms is low(SRC).
Mobility in soil
The Koc of t-butyl alcohol has been reported as 37 (log Koc 1.57)(1-2). According to a classification scheme(3), this Koc value suggests that t-butyl alcohol is expected to have very high mobility in soil.
Other adverse effects
no data available
SECTION 13: Disposal considerations
Disposal methods
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
UN Number
ADR/RID: UN1120 (For reference only, please check.)
IMDG: UN1120 (For reference only, please check.)
IATA: UN1120 (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: BUTANOLS (For reference only, please check.)
IMDG: BUTANOLS (For reference only, please check.)
IATA: BUTANOLS (For reference only, please check.)
Transport hazard class(es)
ADR/RID: 3 (For reference only, please check.)
IMDG: 3 (For reference only, please check.)
IATA: 3 (For reference only, please check.)
Packing group, if applicable
ADR/RID: II (For reference only, please check.)
IMDG: II (For reference only, please check.)
IATA: II (For reference only, please check.)
Environmental hazards
ADR/RID: No
IMDG: No
IATA: No
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
Safety, health and environmental regulations specific for the product in question
SECTION 16: Other information
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Other Information
The odour warning when the exposure limit value is exceeded is insufficient.