(epoxyethyl)benzene SDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
- Product name： (epoxyethyl)benzene
- CAS： 96-09-3
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses： For R&D use only. Not for medicinal, household or other use.
- Uses advised against： none
Company Identification
- Company：Chemicalbook.in
- Address：5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
- Telephone：+91 9550333722
SECTION 2: Hazards identification
Classification of the substance or mixture
Acute toxicity - Category 4, Dermal
Eye irritation, Category 2
Carcinogenicity, Category 1B
GHS label elements, including precautionary statements
-
Pictogram(s)
- Signal word Danger
H312 Harmful in contact with skin
H319 Causes serious eye irritation
H350 May cause cancer
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P264 Wash ... thoroughly after handling.
P203 Obtain, read and follow all safety instructions before use.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P317 Get medical help.
P321 Specific treatment (see ... on this label).
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P318 IF exposed or concerned, get medical advice.
P405 Store locked up.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
Substance
- Chemical name: (epoxyethyl)benzene
- Common names and synonyms: (epoxyethyl)benzene
- CAS number: 96-09-3
- EC number: 202-476-7
- Concentration: 100%
SECTION 4: First aid measures
Description of necessary first-aid measures
Fresh air, rest.
Remove contaminated clothes. Rinse and then wash skin with water and soap.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Rinse mouth. Refer for medical attention .
Most important symptoms/effects, acute and delayed
SYMPTOMS: Symptoms of exposure to this compound may include severe irritation of the skin and eyes, and skin sensitization. It can cause corrosion of tissues. Other symptoms may include burns, irritation of mucous membranes and upper respiratory tract, nausea, vomiting and headaches. Exposure may also cause central nervous system depression, hepatic lesions and pain to the eyes. Symptoms of exposure to a related compound include drying and cracking of the skin on contact, primary irritation to mucosal surfaces, fatigue, weakness, depression, unsteadiness, feeling of drunkenness, abnormal electroencephalograms and one case of toxic retrobulbar neuritis. Chronic exposure to a related compound has caused peripheral neuropathies (distal hypesthesia and decreased nerve conduction velocities). ACUTE/CHRONIC HAZARDS: This compound is corrosive and can cause burns. It may be toxic by ingestion, inhalation or skin absorption. It is absorbed slowly through the skin. It is an irritant and, when heated to decomposition, it emits acrid fumes and toxic fumes of carbon monoxide and carbon dioxide. (NTP, 1992)
Indication of immediate medical attention and special treatment needed, if necessary
Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand-valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR as necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. Aromatic hydrocarbons and related compounds
SECTION 5: Firefighting measures
Suitable extinguishing media
Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. A water spray may also be used. (NTP, 1992)
Specific hazards arising from the chemical
This chemical is combustible. (NTP, 1992)
Special protective actions for fire-fighters
Use powder, foam, carbon dioxide. In case of fire: keep drums, etc., cool by spraying with water. NO direct contact with water.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Personal protection: chemical protection suit including self-contained breathing apparatus. Collect leaking liquid in covered containers. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.
Environmental precautions
Personal protection: chemical protection suit including self-contained breathing apparatus. Collect leaking liquid in covered containers. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.
Methods and materials for containment and cleaning up
PRECAUTIONS FOR "CARCINOGENS": A high-efficiency particulate arrestor (HEPA) or charcoal filters can be used to minimize amt of carcinogen in exhausted air ventilated safety cabinets, lab hoods, glove boxes or animal rooms ... Filter housing that is designed so that used filters can be transferred into plastic bag without contaminating maintenance staff is avail commercially. Filters should be placed in plastic bags immediately after removal ... The plastic bag should be sealed immediately ... The sealed bag should be labelled properly ... Waste liquids ... should be placed or collected in proper containers for disposal. The lid should be secured & the bottles properly labelled. Once filled, bottles should be placed in plastic bag, so that outer surface ... is not contaminated ... The plastic bag should also be sealed & labelled. ... Broken glassware ... should be decontaminated by solvent extraction, by chemical destruction, or in specially designed incinerators. Chemical Carcinogens
SECTION 7: Handling and storage
Precautions for safe handling
NO open flames. NO contact with acids or bases. Above 76°C use a closed system and ventilation. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Separated from acids, bases and food and feedstuffs. Ventilation along the floor.... PRECAUTIONS SHOULD BE TAKEN TO PREVENT EXCESSIVE PRESSURE UNDER STORAGE OR REACTION CONDITIONS & TO RELIEVE SUCH PRESSURE SHOULD IT OCCUR.
SECTION 8: Exposure controls/personal protection
Control parameters
no data available
no data available
Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures, such as personal protective equipment (PPE)
Wear safety goggles or eye protection in combination with breathing protection.
Protective clothing. Protective gloves.
Use local exhaust or breathing protection.
no data available
SECTION 9: Physical and chemical properties and safety characteristics
-
Physical state：
Liquid.
-
Colour：
Colourless.
-
Odour：
Sweet, pleasant
-
Melting point/freezing point：
-35.6 °C.
-
Boiling point or initial boiling point and boiling range：
194.1 °C.
-
Flammability：
Combustible.
-
Lower and upper explosion limit/flammability limit：
no data available
-
Flash point：
74 °C. Atm. press.:1 013 hPa.
-
Auto-ignition temperature：
498 °C.
-
Decomposition temperature：
no data available
-
pH：
no data available
-
Kinematic viscosity：
1.99 cP at 20 deg C
-
Solubility：
less than 1 mg/mL at 67.1° F (NTP, 1992)
-
Partition coefficient n-octanol/water：
log Pow = 1.61.
-
Vapour pressure：
34.9 Pa. Temperature:20 °C.
-
Density and/or relative density：
1.05 g/cm3. Temperature:25 °C.
-
Relative vapour density：
4.14 (vs air)
-
Particle characteristics：
no data available
SECTION 10: Stability and reactivity
Reactivity
The substance may polymerize due to heating above the flash point, under the influence of acids and bases.
Chemical stability
no data available
Possibility of hazardous reactions
On ... basis /of flash point/, it presents hazard of flammability similar to that encountered with ... o-cresol, o-dichlorobenzene, naphthalene, phenol, and dimethylaniline. Definite hazard exists whenever ... /it/ is heated to temperatures at and above the flash point.STYRENE OXIDE is incompatible with oxidizing agents. Also incompatible with acids and bases. Reacts with 4-(4'-nitrobenzyl)pyridine. Polymerizes exothermally and reacts vigorously with compounds possessing a labile hydrogen (e.g. alcohols and amines) in the presence of catalysts such as acids, bases and certain salts (NTP, 1992).
Conditions to avoid
no data available
Incompatible materials
Reacts vigorously with cmpd having labile hydrogen, incl water, in presence of catalysts such as acids, bases, & certain salts
Hazardous decomposition products
no data available
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 - rat - ca. 4 290 mg/kg bw.
- Inhalation: LC50 - rat (male) - > 500 ppm.
- Dermal: LD50 - rabbit (male) - 1 060 mg/kg bw.
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
Evaluation: There is inadequate evidence in humans for the carcinogenicity of styrene-7,8-oxide. There is sufficient evidence in experimental animals for the carcinogenicity of styrene-7,8-oxide. Overall evaluation: Styrene-7,8-oxide is probably carcinogenic to humans (Group 2A).
Reproductive toxicity
No information is available on the reproductive or developmental effects of styrene oxide in humans. Maternal toxicity and increased fetal mortality have been observed in rats and rabbits exposed to styrene oxide by inhalation. Maternal toxicity, increased preimplantation loss of fetuses, reduced fetal weight, and increased incidence of ossification defects were reported in rats. Maternal toxicity and increased frequency of resorptions were reported in rabbits.
STOT-single exposure
The substance is irritating to the eyes and skin. The substance may cause effects on the central nervous system. Exposure could cause lowering of consciousness.
STOT-repeated exposure
This substance is probably carcinogenic to humans.
Aspiration hazard
No indication can be given about the rate at which a harmful concentration of this substance in the air is reached on evaporation at 20°C.
SECTION 12: Ecological information
Toxicity
- Toxicity to fish: LC50 - Cyprinus carpio - 6.9 mg/L - 96 h.
- Toxicity to daphnia and other aquatic invertebrates: EC50 - Daphnia magna - 13 mg/L - 48 h.
- Toxicity to algae: EC50 - Desmodesmus subspicatus (previous name: Scenedesmus subspicatus) - ca. 32 mg/L - 96 h.
- Toxicity to microorganisms: no data available
Persistence and degradability
AEROBIC: Styrene-7,8-oxide, present at 100 mg/L, reached 80-82% of its theoretical BOD in 2 weeks using an activated sludge inoculum at 30 mg/L and the Japanese MITI test(1); however, the test results might be for the hydrolysis product, styrene glycol(SRC).
Bioaccumulative potential
An estimated BCF of 3.5 was calculated in fish for styrene-7,8-oxide(SRC), using a log Kow of 1.61(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC). Hydrolytic half-lives of 0.17, 28 and 40.9 hours have been reported for styrene-7,8-oxide at pH 3, 7, and 9, respectively(4). Hydrolysis is likely to be a more important fate than bioconcentration in aquatic organisms, particularly in acidic waters(SRC).
Mobility in soil
The Koc of styrene-7,8-oxide is estimated as 53(SRC), using a water solubility of 3,000 mg/L(1) and a regression-derived equation(2). According to a classification scheme(3), this estimated Koc value suggests that styrene-7,8-oxide is expected to have very high mobility in soil. Hydrolytic half-lives of 0.17, 28 and 40.9 hours have been reported for styrene-7,8-oxide at pH 3, 7, and 9, respectively(4). Hydrolysis is likely to be a more important fate than transport through soils, particularly in acidic soils(SRC).
Other adverse effects
no data available
SECTION 13: Disposal considerations
Disposal methods
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
UN Number
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Transport hazard class(es)
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Packing group, if applicable
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Environmental hazards
ADR/RID: No
IMDG: No
IATA: No
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
Safety, health and environmental regulations specific for the product in question
SECTION 16: Other information
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Other Information
Do NOT take working clothes home.