Resorcinol SDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
- Product name： Resorcinol
- CAS： 108-46-3
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses： For R&D use only. Not for medicinal, household or other use.
- Uses advised against： none
Company Identification
- Company：Chemicalbook.in
- Address：5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
- Telephone：+91 9550333722
SECTION 2: Hazards identification
Classification of the substance or mixture
Acute toxicity - Category 4, Oral
Skin irritation, Category 2
Eye irritation, Category 2
Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1
GHS label elements, including precautionary statements
-
Pictogram(s)
- Signal word Warning
H302 Harmful if swallowed
H315 Causes skin irritation
H319 Causes serious eye irritation
H400 Very toxic to aquatic life
P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P273 Avoid release to the environment.
P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P391 Collect spillage.
none
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
Substance
- Chemical name: Resorcinol
- Common names and synonyms: Resorcinol
- CAS number: 108-46-3
- EC number: 203-585-2
- Concentration: 100%
SECTION 4: First aid measures
Description of necessary first-aid measures
Fresh air, rest. Artificial respiration may be needed. Refer for medical attention.
Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention .
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Give a slurry of activated charcoal in water to drink. Refer for medical attention .
Most important symptoms/effects, acute and delayed
Inhalation of vapors or dust causes irritation of respiratory tract. Ingestion causes burns of mucous membranes, severe diarrhea, pallor, sweating, weakness, headache, dizziness, tinnitus, shock, and severe convulsions; may also cause siderosis of the spleen and tubular injury to the kidney. Contact with eyes causes irritation. Can be absorbed from wounds or through unbroken skin, producing severe dermatitis, methemoglobinemia, cyanosis, convulsions, tachycardia, dyspnea, and death. (USCG, 1999)
Indication of immediate medical attention and special treatment needed, if necessary
Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand-valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR as necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. Phenols and related compounds
SECTION 5: Firefighting measures
Suitable extinguishing media
If material on fire or involved in fire: Extinguish fire using agent suitable for type of surrounding fire (Material itself does not burn or burns with difficulty). Use water in flooding quantities as fog.
Specific hazards arising from the chemical
Behavior in Fire: Containers may explode. (USCG, 1999)
Special protective actions for fire-fighters
Use water spray, powder.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Personal protection: P2 filter respirator for harmful particles. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.
Environmental precautions
Personal protection: P2 filter respirator for harmful particles. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.
Methods and materials for containment and cleaning up
Environmental consideration: Water spill: Use mechanical dredges or lifts to remove immobilized masses of pollutants and precipitates.
SECTION 7: Handling and storage
Precautions for safe handling
NO open flames. Prevent build-up of electrostatic charges (e.g., by grounding). Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Separated from incompatible materials and food and feedstuffs. See Chemical Dangers.Separated from incompatible materials and food and feedstuffs.
SECTION 8: Exposure controls/personal protection
Control parameters
TLV: 10 ppm as TWA; 20 ppm as STEL; A4 (not classifiable as a human carcinogen).MAK: sensitization of skin (SH).EU-OEL: 45 mg/m3, 10 ppm as TWA; (skin)
no data available
Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures, such as personal protective equipment (PPE)
Wear safety goggles, face shield or eye protection in combination with breathing protection.
Protective gloves. Protective clothing.
Use local exhaust or breathing protection.
no data available
SECTION 9: Physical and chemical properties and safety characteristics
-
Physical state：
Solid. Flakes.
-
Colour：
White-slightly colored flake.
-
Odour：
Faint, characteristic odor
-
Melting point/freezing point：
110 °C.
-
Boiling point or initial boiling point and boiling range：
277.5 °C. Atm. press.:1 013 hPa.
-
Flammability：
Class IIIB Combustible Liquid: Fl.P. at or above 200°F., but may be difficult to ignite.
-
Lower and upper explosion limit/flammability limit：
Lower flammable limit: 1.4% at 392 deg F (200 deg C) by volume; Upper flammable limit: 1.28% by volume
-
Flash point：
127 °C.
-
Auto-ignition temperature：
>= 605 - <= 608 °C. Remarks:Handbook data/ published data; data on pressure was . Assumed to be 1013 hPa.
-
Decomposition temperature：
no data available
-
pH：
4.5. Remarks:10% aqueous solution, temperature not provided.
-
Kinematic viscosity：
not stated = 31. Temperature:150.0°C.;not stated = 38. Temperature:140.0°C.
-
Solubility：
Miscible with water
-
Partition coefficient n-octanol/water：
log Pow = 0.8. Temperature:20 °C. Remarks:Published data, pH is not reported.
-
Vapour pressure：
0.001 hPa. Temperature:25 °C.
-
Density and/or relative density：
1.28 g/cm3. Temperature:20 °C.
-
Relative vapour density：
3.79 (NTP, 1992) (Relative to Air)
-
Particle characteristics：
no data available
SECTION 10: Stability and reactivity
Reactivity
Reacts with strong oxidants, ammonia and amino compounds. This generates fire and explosion hazard.
Chemical stability
Hygroscopic
Possibility of hazardous reactions
Combustible when exposed to heat or flameAs a result of flow, agitation, etc., electrostatic charges can be generated.RESORCINOL is a weak organic acid. Incompatible with acetanilide, albumin, alkalis, antipyrine, camphor, iron salts, menthol, spirit nitrous ether, and urethane. Can react with oxidizing materials (NTP, 1992). Has a potentially explosive reaction with concentrated nitric acid [Lewis]. Turns pink on contact with iron.
Conditions to avoid
no data available
Incompatible materials
Can react with oxidizing materials
Hazardous decomposition products
When heated to decomposition it emits acrid smoke and irritating fumes.
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 - rat (male/female) - 510 mg/kg bw.
- Inhalation: LC0 - rat (female) - > 7 800 mg/m3 air.
- Dermal: LD50 - rabbit (male) - 2 830 mg/kg bw.
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
Evaluation: No epidemiological data relevant to the carcinogenicity of resorcinol were available. There is inadequate evidence in experimental animals for the carcinogenicity of resorcinol. Overall evaluation: Resorcinol is not classifiable as to its carcinogenicity to humans (Group 3).
Reproductive toxicity
no data available
STOT-single exposure
The substance is irritating to the eyes, skin and respiratory tract. The substance may cause effects on the blood. This may result in the formation of methaemoglobin. The effects may be delayed. Medical observation is indicated.
STOT-repeated exposure
Repeated or prolonged contact may cause skin sensitization in rare cases.
Aspiration hazard
A harmful contamination of the air will not or will only very slowly be reached on evaporation of this substance at 20°C; on spraying or dispersing, however, much faster.
SECTION 12: Ecological information
Toxicity
- Toxicity to fish: LC50 - Pimephales promelas - 29.5 mg/L - 96 h.
- Toxicity to daphnia and other aquatic invertebrates: LC50 - Daphnia magna - 1 mg/L - 48 h.
- Toxicity to algae: EC50 - Pseudokirchneriella subcapitata (previous names: Raphidocelis subcapitata, Selenastrum capricornutum) - > 97 mg/L - 72 h.
- Toxicity to microorganisms: EC50 - activated sludge of a predominantly domestic sewage - 79 mg/L - 3 h.
Persistence and degradability
AEROBIC: Resorcinol, present at 100 mg/L, reached 100% of its theoretical BOD in 2 weeks using an activated sludge inoculum at 30 mg/L in the Japanese MITI test(1,-3). Complete degradation of resorcinol occurred in 8 days (as determined by a 100% UV absorbancy loss) in a mineral salts medium using a silt loam soil inocula(4). A 5-day 61% theoretical BOD was measured using a sewage inocula(5). A 95% degradation was observed over a 0.4-day incubation period using a Warburg respirometer and an acclimated activated sludge inocula(6). A 6-day 21% theoretical BOD was observed using a Warburg respirometer and an activated sludge acclimated to aniline(7). A 12-hr theoretical BOD of 33-39% was observed using a Warburg respirometer and activated sludge acclimated to either phenol, catechol, or benzoic acid(8). A 5-day COD removal of 90% was measured in an activated sludge system(9). The half-life of resorcinol in an aerobic screening test ranged from 0.16 to 0.24 days using activated sludge acclimated to cresols(10). Half-lives of 0.5 and 4.5 hours were determined for initial concentrations of 20 and 120 ppm resorcinol, respectively, in a treatment plant simulation study over a 1-hr incubation period using inoculum from a coke wastewater treatment plant(11). Degradation of 95% in 1 day and 90% in 8 days was observed in a biological treatment simulation using activated sludge and initial concns of 138 and 500 ppm, respectively(12). Using a Warburg respirometer and a mixed-culture of bacteria adapted to phenol, 95% of initial resorcinol was degraded in 1 to 2 days(13). Resorcinol, present at 2 mg/L, reached 68.6% of its theoretical BOD in 5 days, using 150 mL of river water in the river die-away test. The source of river water inoculum was the Songhua River, Jilan Province, China, which is contaminated with substituted benzenes(14).
Bioaccumulative potential
An estimated BCF of 3 was calculated in fish for resorcinol(SRC), using a log Kow of 0.80(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).
Mobility in soil
The Koc of resorcinol in a clay loam soil from the Michigan State University Soils Research Farm was measured to be 10.36(1). According to a classification scheme(2), this estimated Koc value suggests that resorcinol is expected to have very high mobility in soil. The pKa1 of resorcinol is 9.30(3), indicating that this compound will exist partially in the anion form in the environment and anions generally do not adsorb more strongly to soils containing organic carbon and clay than their neutral counterparts(4).
Other adverse effects
no data available
SECTION 13: Disposal considerations
Disposal methods
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
UN Number
ADR/RID: UN2876 (For reference only, please check.)
IMDG: UN2876 (For reference only, please check.)
IATA: UN2876 (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: RESORCINOL (For reference only, please check.)
IMDG: RESORCINOL (For reference only, please check.)
IATA: RESORCINOL (For reference only, please check.)
Transport hazard class(es)
ADR/RID: 6.1 (For reference only, please check.)
IMDG: 6.1 (For reference only, please check.)
IATA: 6.1 (For reference only, please check.)
Packing group, if applicable
ADR/RID: III (For reference only, please check.)
IMDG: III (For reference only, please check.)
IATA: III (For reference only, please check.)
Environmental hazards
ADR/RID: Yes
IMDG: Yes
IATA: Yes
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
Safety, health and environmental regulations specific for the product in question
SECTION 16: Other information
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Other Information
Depending on the degree of exposure, periodic medical examination is indicated.Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.Do NOT take working clothes home.