Propionic acid SDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
- Product name： Propionic acid
- CAS： 79-09-4
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses： For R&D use only. Not for medicinal, household or other use.
- Uses advised against： none
Company Identification
- Company：Chemicalbook.in
- Address：5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
- Telephone：+91 9550333722
SECTION 2: Hazards identification
Classification of the substance or mixture
Skin corrosion, Sub-category 1B
GHS label elements, including precautionary statements
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Pictogram(s)
- Signal word Danger
H314 Causes severe skin burns and eye damage
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash ... thoroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P363 Wash contaminated clothing before reuse.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P316 Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P405 Store locked up.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
Substance
- Chemical name: Propionic acid
- Common names and synonyms: Propionic acid
- CAS number: 79-09-4
- EC number: 201-176-3
- Concentration: 100%
SECTION 4: First aid measures
Description of necessary first-aid measures
Fresh air, rest. Half-upright position. Refer for medical attention.
Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention .
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Rinse mouth. Do NOT induce vomiting. Give one or two glasses of water to drink. Refer for medical attention .
Most important symptoms/effects, acute and delayed
Liquid causes skin and eye burns. Vapors may irritate eeyes, nose, and throat, but should not cause systemic illness. (USCG, 1999)
Indication of immediate medical attention and special treatment needed, if necessary
Basic treatment: Establish a patent airway. Suction if necessary. Watch for signs of respiratory insufficiency and assist respirations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary ... Monitor for shock and treat if necessary ... For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport ... Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool. Activated charcoal is not effective ... Do not attempt to neutralize because of exothermic reaction. Cover skin bumps with dry, sterile dressings after decontamination ... Organic acids and related compounds
SECTION 5: Firefighting measures
Suitable extinguishing media
Use water spray, dry chemical, "alcohol resistant" foam, or carbon dioxide. Use water spray to keep fire-exposed containers cool.
Specific hazards arising from the chemical
Excerpt from ERG Guide 132 [Flammable Liquids - Corrosive]: Flammable/combustible material. May be ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Those substances designated with a (P) may polymerize explosively when heated or involved in a fire. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water. (ERG, 2016)
Special protective actions for fire-fighters
Use water spray, powder, alcohol-resistant foam, carbon dioxide. In case of fire: keep drums, etc., cool by spraying with water.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. Do NOT let this chemical enter the environment. Personal protection: chemical protection suit including self-contained breathing apparatus.
Environmental precautions
Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. Do NOT let this chemical enter the environment. Personal protection: chemical protection suit including self-contained breathing apparatus.
Methods and materials for containment and cleaning up
Use water spray to cool and disperse vapors, protect personnel, and dilute spills to form nonflammable mixtures. Control runoff and isolate discharged material for proper disposal.
SECTION 7: Handling and storage
Precautions for safe handling
NO open flames, NO sparks and NO smoking. Above 54°C use a closed system, ventilation and explosion-proof electrical equipment. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Fireproof. Separated from strong oxidants, strong bases and food and feedstuffs.Outside or detached storage is preferred. Store in a cool, dry, well-ventilated location.
SECTION 8: Exposure controls/personal protection
Control parameters
TLV: 10 ppm as TWA.MAK: 31 mg/m3, 10 ppm; peak limitation category: I(2); pregnancy risk group: C.EU-OEL: 31 mg/m3, 10 ppm as TWA; 62 mg/m3, 20 ppm as STEL
no data available
Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures, such as personal protective equipment (PPE)
Wear face shield.
Protective gloves. Protective clothing.
Use ventilation, local exhaust or breathing protection.
no data available
SECTION 9: Physical and chemical properties and safety characteristics
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Physical state：
Liquid.
-
Colour：
Clear, colorless.
-
Odour：
Slightly pungent disagreeable, rancid odor
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Melting point/freezing point：
-21.5 °C.
-
Boiling point or initial boiling point and boiling range：
140.7 - 141.4 °C. Atm. press.:1 013 hPa.
-
Flammability：
Class II Combustible Liquid: Fl.P. at or above 100°F and below 140°F.
-
Lower and upper explosion limit/flammability limit：
Lower flammable limit: 2.9% by volume; Upper flammable limit: 12.1% by volume
-
Flash point：
53 °C. Atm. press.:1 013.25 hPa.
-
Auto-ignition temperature：
440 °C. Atm. press.:1 013 hPa.
-
Decomposition temperature：
no data available
-
pH：
no data available
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Kinematic viscosity：
dynamic viscosity (in mPa s) = 1.102. Temperature:20°C. Remarks:Staudinger; Bauer.;dynamic viscosity (in mPa s) = 0.84. Temperature:20°C. Remarks:Kohler, Friedrich; Atrops, H.; Kalali, H.; Liebermann, E.; Wilhelm, Emmerich; et al.
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Solubility：
Miscible with water
-
Partition coefficient n-octanol/water：
log Pow = 0.33. Remarks:No experimental values for the temperature and pH are available.
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Vapour pressure：
3.9 hPa. Temperature:20 °C.
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Density and/or relative density：
0.99 g/cm3. Temperature:20 °C.
-
Relative vapour density：
2.55 (vs air)
-
Particle characteristics：
no data available
SECTION 10: Stability and reactivity
Reactivity
The substance is a medium strong acid. Reacts with bases, strong oxidants and amines. This generates fire and explosion hazard. Attacks many metals. This produces flammable/explosive gas (hydrogen - see ICSC 0001).
Chemical stability
no data available
Possibility of hazardous reactions
Flammable liquid. Highly flammable when exposed to heat, flame, or oxidizers.PROPIONIC ACID is a colorless, oily liquid, moderately toxic, corrosive. Flammable when exposed to heat, flame or oxidizers. When heated to decomposition it emits acrid smoke and irritating fumes [Lewis, 3rd ed., 1993, p. 1090].
Conditions to avoid
no data available
Incompatible materials
Alkalis, strong oxidizers (e.g., chromium trioxide) [Note: Corrosive to steel].
Hazardous decomposition products
When heated to decomposition it emits acrid smoke and irritating fumes.
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 - rat (male/female) - 3 455.1 mg/kg bw. Remarks:At all doses symptoms included: apathy, dyspnoea, partly cyanosis, intermittent breathing, crouching position, agitation.
- Inhalation: LC50 - rat (male/female) - > 19.7 mg/L air.
- Dermal: LD50 - rat (female) - 3 235 mg/kg bw.
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
no data available
Reproductive toxicity
no data available
STOT-single exposure
The substance is corrosive to the eyes, skin and respiratory tract.
STOT-repeated exposure
no data available
Aspiration hazard
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C.
SECTION 12: Ecological information
Toxicity
- Toxicity to fish: LC50 - Leuciscus idus - > 10 000 mg/L - 96 h.
- Toxicity to daphnia and other aquatic invertebrates: EC50 - Daphnia magna - > 500 mg/L - 48 h.
- Toxicity to algae: EC50 - Desmodesmus subspicatus (previous name: Scenedesmus subspicatus) - > 500 mg/L - 72 h.
- Toxicity to microorganisms: EC20 - activated sludge, domestic - 500 - 1 040 mg/L - 30 min. Remarks:Respiration rate.
Persistence and degradability
AEROBIC: a number of aerobic biological screening studies, which utilized settled waste water, sewage, or activated sludge for inocula, have demonstrated that propionic acid is readily biodegradable(1-14). For example, 5 day theoretical BOD's of 23-55%(6), 37%(15), 40%(9) and 71%(2) have been reported. These studies indicate propionic acid should degrade rapidly under most environmental conditions.
Bioaccumulative potential
An estimated BCF of 3.2 was calculated for propionic acid(SRC), using a log Kow of 0.33(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low.
Mobility in soil
The Koc of propionic acid is estimated as 36(SRC), using a log Kow of 0.33(1) and a regression-derived equation(2). According to a classification scheme(3), this estimated Koc value suggests that propionic acid is expected to have very high mobility in soil. The pKa of propionic acid is 4.87(4), indicating that this compound will primarily exist in anion form in the environment and anions generally do not adsorb more strongly to soils containing organic carbon and clay than their neutral counterparts(5).
Other adverse effects
no data available
SECTION 13: Disposal considerations
Disposal methods
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
UN Number
ADR/RID: UN1848 (For reference only, please check.)
IMDG: UN1848 (For reference only, please check.)
IATA: UN1848 (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: PROPIONIC ACID with not less than 10% and less than 90% acid by mass (For reference only, please check.)
IMDG: PROPIONIC ACID with not less than 10% and less than 90% acid by mass (For reference only, please check.)
IATA: PROPIONIC ACID with not less than 10% and less than 90% acid by mass (For reference only, please check.)
Transport hazard class(es)
ADR/RID: 8 (For reference only, please check.)
IMDG: 8 (For reference only, please check.)
IATA: 8 (For reference only, please check.)
Packing group, if applicable
ADR/RID: III (For reference only, please check.)
IMDG: III (For reference only, please check.)
IATA: III (For reference only, please check.)
Environmental hazards
ADR/RID: No
IMDG: No
IATA: No
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
Safety, health and environmental regulations specific for the product in question
SECTION 16: Other information
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/