2,4,6-trimethyl-1,3,5-trioxane SDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
- Product name： 2,4,6-trimethyl-1,3,5-trioxane
- CAS： 123-63-7
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses： For R&D use only. Not for medicinal, household or other use.
- Uses advised against： none
Company Identification
- Company：Chemicalbook.in
- Address：5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
- Telephone：+91 9550333722
SECTION 2: Hazards identification
Classification of the substance or mixture
Flammable liquids, Category 3
GHS label elements, including precautionary statements
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Pictogram(s)
- Signal word Warning
H226 Flammable liquid and vapour
P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P233 Keep container tightly closed.
P240 Ground and bond container and receiving equipment.
P241 Use explosion-proof [electrical/ventilating/lighting/...] equipment.
P242 Use non-sparking tools.
P243 Take action to prevent static discharges.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P303+P361+P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse affected areas with water [or shower].
P370+P378 In case of fire: Use ... to extinguish.
P403+P235 Store in a well-ventilated place. Keep cool.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
Substance
- Chemical name: 2,4,6-trimethyl-1,3,5-trioxane
- Common names and synonyms: 2,4,6-trimethyl-1,3,5-trioxane
- CAS number: 123-63-7
- EC number: 204-639-8
- Concentration: 100%
SECTION 4: First aid measures
Description of necessary first-aid measures
Fresh air, rest. Refer for medical attention.
Remove contaminated clothes. Rinse and then wash skin with water and soap.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Do NOT induce vomiting. Give one or two glasses of water to drink. Refer for medical attention .
Most important symptoms/effects, acute and delayed
INHALATION AND INGESTION: Irritation, headache, bronchitis, pulmonary edema. Irritating to digestive tract. Hypnotic and analgesic properties. Incoordination and drowsiness, followed by sleep. Larger doses-coma-weak pulse and shallow respiration, cyanosis-death from respiratory paralysis. EYES: irritation-can cause serious injury. SKIN: Dermatitis (skin inflammation). (USCG, 1999)
Indication of immediate medical attention and special treatment needed, if necessary
Treatment is directed toward maintenance of airway, breathing, and circulation. Supportive care is the mainstay of therapy. Patients are often critically ill and must be under constant supervision.
SECTION 5: Firefighting measures
Suitable extinguishing media
Use water spray, dry chemical, "alcohol resistant" foam, or carbon dioxide. Water may be ineffective. Use water spray to keep fire exposed containers cool. Approach fire from upwind to avoid hazardous vapors and toxic decomposition products.
Specific hazards arising from the chemical
Special Hazards of Combustion Products: Emits toxic fumes on heating. Behavior in Fire: Can react vigorously when exposed to heat or flame. Vapor is heavier than air and may travel a considerable distance to source of ignition and flash back. (USCG, 1999)
Special protective actions for fire-fighters
Use water spray, alcohol-resistant foam, dry powder, carbon dioxide. In case of fire: keep drums, etc., cool by spraying with water.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Remove all ignition sources. Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Collect leaking and spilled liquid in sealable non-plastic containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.
Environmental precautions
Remove all ignition sources. Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Collect leaking and spilled liquid in sealable non-plastic containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.
Methods and materials for containment and cleaning up
Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.
SECTION 7: Handling and storage
Precautions for safe handling
NO open flames, NO sparks and NO smoking. Above 24°C use a closed system, ventilation and explosion-proof electrical equipment. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Fireproof. Separated from food and feedstuffs, bases and oxidants.PARALDEHYDE SHOULD BE STORED IN WELL-FILLED, TIGHT, LIGHT-RESISTANT GLASS CONTAINERS WITH A CAPACITY OF NO MORE THAN 30 ML, AT A TEMP NOT EXCEEDING 25 DEG C.
SECTION 8: Exposure controls/personal protection
Control parameters
no data available
no data available
Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures, such as personal protective equipment (PPE)
Wear safety spectacles or eye protection in combination with breathing protection.
Protective gloves.
Use ventilation, local exhaust or breathing protection.
no data available
SECTION 9: Physical and chemical properties and safety characteristics
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Physical state：
Liquid. Liquid.
-
Colour：
Light yellow.
-
Odour：
CHARACTERISTIC AROMATIC ODOR
-
Melting point/freezing point：
12.6 °C
-
Boiling point or initial boiling point and boiling range：
124.5 °C
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Flammability：
Highly flammable.
-
Lower and upper explosion limit/flammability limit：
LOWER LIMIT, 1.3%.
-
Flash point：
24 °C
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Auto-ignition temperature：
460° F (USCG, 1999)
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Decomposition temperature：
no data available
-
pH：
no data available
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Kinematic viscosity：
1.128 centipoise at 70 deg F
-
Solubility：
120 g / L (20 °C)
-
Partition coefficient n-octanol/water：
Log Kow = 0.67
-
Vapour pressure：
25.89 psi ( 55 °C)
-
Density and/or relative density：
0.99
-
Relative vapour density：
1.52 (vs air)
-
Particle characteristics：
no data available
SECTION 10: Stability and reactivity
Reactivity
Decomposes on heating. This produces toxic fumes. Decomposes under the influence of air and light. Reacts with bases and oxidants. Attacks plastics.
Chemical stability
On exposure to light & air, it decomp to acetaldehyde & is oxidized to acetic acid
Possibility of hazardous reactions
DANGEROUS, WHEN EXPOSED TO HEAT, FLAME OR OXIDIZERS.The vapour is heavier than air and may travel along the ground; distant ignition possible.PARALDEHYDE is an ether derivative. This compound is decomposed by light and air, on prolonged storage, to acetaldehyde and acetic acid. Incompatible with alkalis, hydrocyanic acid iodides and oxidizers. (NTP, 1992)
Conditions to avoid
no data available
Incompatible materials
Paraldehyde is incompatible with many plastics
Hazardous decomposition products
Emits toxic fumes on heating.
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 - rat (male/female) - 2 711 mg/kg bw.
- Inhalation: no data available
- Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
no data available
Reproductive toxicity
no data available
STOT-single exposure
The substance is irritating to the eyes, skin and respiratory tract. The substance may cause effects on the central nervous system.
STOT-repeated exposure
The substance may have effects on the nervous system. This may result in addiction. The substance may have effects on the kidneys and liver. This may result in impaired functions.
Aspiration hazard
No indication can be given about the rate at which a harmful concentration of this substance in the air is reached on evaporation at 20°C.
SECTION 12: Ecological information
Toxicity
- Toxicity to fish: LC50 - Oncorhynchus mykiss (previous name: Salmo gairdneri) - 1 340 mg/L - 96 h.
- Toxicity to daphnia and other aquatic invertebrates: EC50 - Daphnia magna - 356 mg/L - 48 h.
- Toxicity to algae: no data available
- Toxicity to microorganisms: EC10 - Pseudomonas putida - > 1 000 mg/L - 18 h.
Persistence and degradability
Japanese MITI, initial concn 100 ppm, 14 days <30% BODT, activated sludge inoculum(1). A bacterium isolated from sewage, C. paraldehydium KY 4359, was found to degrade paraldehyde to acetaldehyde and acetic acid(2).
Bioaccumulative potential
Based on a water solubility of 125,000 mg/l at 25 deg C and a log Kow of 0.67, bioconcentration factors (BCF) of 0.8-2 were estimated for paraldehyde(1,2,3,SRC). These BCF values suggest that paraldehyde would not bioaccumulate significantly in aquatic organisms(SRC).
Mobility in soil
Soil adsorption coefficients (Koc) of 7-55 were estimated for paraldehyde using linear regression equations based on a water solubility of 125,000 mg/l at 25 deg C and a log Kow of 0.67(1,2,3,SRC). These Koc values suggest that paraldehyde would be very highly mobile in soil and that adsorption to suspended solids and sediments in water would be insignificant(4,SRC).
Other adverse effects
no data available
SECTION 13: Disposal considerations
Disposal methods
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
UN Number
ADR/RID: UN1264 (For reference only, please check.)
IMDG: UN1264 (For reference only, please check.)
IATA: UN1264 (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: PARALDEHYDE (For reference only, please check.)
IMDG: PARALDEHYDE (For reference only, please check.)
IATA: PARALDEHYDE (For reference only, please check.)
Transport hazard class(es)
ADR/RID: 3 (For reference only, please check.)
IMDG: 3 (For reference only, please check.)
IATA: 3 (For reference only, please check.)
Packing group, if applicable
ADR/RID: III (For reference only, please check.)
IMDG: III (For reference only, please check.)
IATA: III (For reference only, please check.)
Environmental hazards
ADR/RID: No
IMDG: No
IATA: No
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
Safety, health and environmental regulations specific for the product in question
SECTION 16: Other information
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/