Prometon SDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
- Product name： Prometon
- CAS： 1610-18-0
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses： For R&D use only. Not for medicinal, household or other use.
- Uses advised against： none
Company Identification
- Company：Chemicalbook.in
- Address：5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
- Telephone：+91 9550333722
SECTION 2: Hazards identification
Classification of the substance or mixture
Acute toxicity - Category 4, Oral
Skin irritation, Category 2
Eye irritation, Category 2
Specific target organ toxicity – single exposure, Category 3
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 2
GHS label elements, including precautionary statements
-
Pictogram(s)
- Signal word Warning
H302 Harmful if swallowed
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
H411 Toxic to aquatic life with long lasting effects
P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P273 Avoid release to the environment.
P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P319 Get medical help if you feel unwell.
P391 Collect spillage.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
Substance
- Chemical name: Prometon
- Common names and synonyms: Prometon
- CAS number: 1610-18-0
- EC number: 216-548-0
- Concentration: 100%
SECTION 4: First aid measures
Description of necessary first-aid measures
Move the victim into fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration and consult a doctor immediately. Do not use mouth to mouth resuscitation if the victim ingested or inhaled the chemical.
Take off contaminated clothing immediately. Wash off with soap and plenty of water. Consult a doctor.
Rinse with pure water for at least 15 minutes. Consult a doctor.
Rinse mouth with water. Do not induce vomiting. Never give anything by mouth to an unconscious person. Call a doctor or Poison Control Center immediately.
Most important symptoms/effects, acute and delayed
no data available
Indication of immediate medical attention and special treatment needed, if necessary
Basic Treatment: Establish a patent airway (oropharyngeal or nasopharyngeal airway, if needed). Suction if necessary. Encourage patient to take deep breaths. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary . Monitor for shock and treat if necessary . Anticipate seizures and treat if necessary . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with 0.9% saline (NS) during transport . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool . Irritating materials
SECTION 5: Firefighting measures
Suitable extinguishing media
Extinguish fire using agent suitable for type of surrounding fire. ... Use water in flooding quantities as fog. Use "alcohol foam" ... Wear positive pressure self-contained breathing apparatus when fighting fires involving this material. Triazine pesticide (compounds and preparations), solid (insecticides, agricultural, not elsewhere classified, other than liquid)
Specific hazards arising from the chemical
no data available
Special protective actions for fire-fighters
Wear self-contained breathing apparatus for firefighting if necessary.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Avoid dust formation. Avoid breathing mist, gas or vapours.Avoid contacting with skin and eye. Use personal protective equipment.Wear chemical impermeable gloves. Ensure adequate ventilation.Remove all sources of ignition. Evacuate personnel to safe areas.Keep people away from and upwind of spill/leak.
Environmental precautions
Prevent further spillage or leakage if it is safe to do so. Do not let the chemical enter drains. Discharge into the environment must be avoided.
Methods and materials for containment and cleaning up
For minor spills. leaks, etc.. follow all precautions indicated on /the pesticide/ label and clean up immediately. Take special care to avoid contamination of equipment and facilities during cleanup procedures and disposal of wastes. In the event of a major spill, fire, or other emergency, call 1-800-535-5053 (INFOTRAC). day or night. Pramitol 4RR
SECTION 7: Handling and storage
Precautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Do not contaminate water, food. or feed by storage ... Store at temperatures above 32 deg F./Pramitol 4RR/
SECTION 8: Exposure controls/personal protection
Control parameters
no data available
no data available
Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures, such as personal protective equipment (PPE)
Wear tightly fitting safety goggles with side-shields conforming to EN 166(EU) or NIOSH (US).
Wear fire/flame resistant and impervious clothing. Handle with gloves. Gloves must be inspected prior to use. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.
If the exposure limits are exceeded, irritation or other symptoms are experienced, use a full-face respirator.
no data available
SECTION 9: Physical and chemical properties and safety characteristics
-
Physical state：
no data available
-
Colour：
Colorless powder
-
Odour：
no data available
-
Melting point/freezing point：
91 to 92 deg C
-
Boiling point or initial boiling point and boiling range：
359°C at 760mmHg
-
Flammability：
no data available
-
Lower and upper explosion limit/flammability limit：
no data available
-
Flash point：
170.9°C
-
Auto-ignition temperature：
no data available
-
Decomposition temperature：
no data available
-
pH：
no data available
-
Kinematic viscosity：
no data available
-
Solubility：
READILY SOL IN CHLOROFORM
-
Partition coefficient n-octanol/water：
log Kow = 2.99
-
Vapour pressure：
2.45E-05mmHg at 25°C
-
Density and/or relative density：
1.133g/cm3
-
Relative vapour density：
no data available
-
Particle characteristics：
no data available
SECTION 10: Stability and reactivity
Reactivity
no data available
Chemical stability
Stable to hydrolysis @ 20 deg C in neutral, alkaline or slightly acidic media. ...
Possibility of hazardous reactions
Nonflammable.
Conditions to avoid
no data available
Incompatible materials
no data available
Hazardous decomposition products
Decomposed by uv radiation.
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 Rat oral 2980 mg/kg Technical
- Inhalation: LC50 Rat inhalation > 3.26 mg/l/4 hr Technical
- Dermal: LD50 Rabbit percutaneous > 2000 mg/kg Technical
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
Cancer Classification: Group D Not Classifiable as to Human Carcinogenicity
Reproductive toxicity
no data available
STOT-single exposure
no data available
STOT-repeated exposure
no data available
Aspiration hazard
no data available
SECTION 12: Ecological information
Toxicity
- Toxicity to fish: LC50 Salmo gairdneri (Rainbow trout) 20 ppm/96 hr /Technical; conditions of bioassay not specified
- Toxicity to daphnia and other aquatic invertebrates: EC50; Species: Daphnia magna (Water flea, age <24 hr); Conditions: freshwater, static, 21 deg C; Concentration: 78000 ug/L for 24 hr; Effect: intoxication, immobilization /96-99.9% purity
- Toxicity to algae: EC50; Species: Pseudokirchneriella subcapitata (Green algae) Conditions: freshwater, static; Concentration: 98 ug/L for 5 days (95% confidence interval: 88-108 ug/L); Effect: population abundance /97% purity
- Toxicity to microorganisms: no data available
Persistence and degradability
AEROBIC: In one investigation, no changes in phytotoxicity were observed in moist, organic soil treated with 17.5 ppm of prometon after 8 wk of incubation; the soil was adjusted to four pHs: 4.3, 5.3, 6.5, and 7.5(1). Several soil bacteria and fungi are reported to attack prometon(2). However, it is not known whether biodegradation is the primary degradation process in soil(2). Methoxy-s-triazines are more resistant to biodegradation than the corresponding methylthio- and chloro-s-triazines(2). Average soil half-life is reported as 932 days(3). In soil, microbial degradation involves hydrolytic cleavage of the methoxy group to give hydroxy metabolites, and dealkylation of the side chains(4). Persistence in soil can be as much as one year, depending upon soil type, moisture, and the application rate(4).
Bioaccumulative potential
An estimated BCF of 19 was calculated in fish for prometon(SRC), using a log Kow of 2.99(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).
Mobility in soil
A mean Koc of 524.3 was reported for prometon in 29 soils(1). The Freundlich adsorption constant, K, and exponent, 1/n, for prometon on San Joaquin sandy loam (0.72% organic carbon, 9.7% clay, pH 6.2) at 25 deg C were 2.94 and 0.81, respectively; the corresponding Koc is 408 at a concn of 1 ppm and 305 at a concn of 10.3 ppm(2). Koc values of 572 and 395 were determined in Hanford sandy loam (0.43% organic C, pH 6.05, 7.1% clay, 25.8% silt, 67.1% sand) and Tujunga loamy sand (0.33% organic C, pH 6.3, 4.5% clay, 13.5% silt, 82.0% sand), respectively(3). According to a classification scheme(4), these Koc values suggest that prometon is expected to have low to moderate mobility in soil(SRC). Only 0.1% of prometon applied to a 30.5 cm column and leached under unsaturated flow conditions with 1.2 cm of water/day, was found in leachate at the end of 30 days(5). Prometon was included in mobility class 3, on a scale from 1 (immobile) to 5 (very mobile)(6). Prometon is adsorbed onto soil humic acid, forming stable complexes(7). Ionic, hydrogen bonding, electron donor-acceptor, and covalent forces contribute to the binding. The fact that the basicity of several s-triazines, and hence their tendency to form ionic bonds, is not correlated with adsorptivity indicate that ionic bonding is not the primary factor governing adsorption(7). Data on the free radical content of humic acid adducts, demonstrate that electron donor-acceptor forces are particularly important in the binding of prometon to soil(7). The Freundlich adsorption constant, K, and exponent, 1/n, for prometon on Volcay bentonite at 25 deg C was 150 and 0.64, respectively(8). The mean sorption coefficient (Kd) of 4.86 was given for 59 measured values(9). A pKa of 4.3 at 21 deg C(10) indicates prometon will exist predominately in the unionized form under environmental pHs(SRC). Max adsorption of prometon onto soil organic matter occurred in the pH range 4.2 to 5.2; the addition of HCl or NaOH decreased adsorption(11). Approximately 52% of the prometon adsorbed by organic matter was desorbed with two extractions of 0.1 N NaCl(11).
Other adverse effects
no data available
SECTION 13: Disposal considerations
Disposal methods
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
UN Number
ADR/RID: no data available
IMDG: no data available
IATA: no data available
UN Proper Shipping Name
ADR/RID: no data available
IMDG: no data available
IATA: no data available
Transport hazard class(es)
ADR/RID: no data available
IMDG: no data available
IATA: no data available
Packing group, if applicable
ADR/RID: no data available
IMDG: no data available
IATA: no data available
Environmental hazards
ADR/RID: Yes
IMDG: Yes
IATA: Yes
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
Safety, health and environmental regulations specific for the product in question
SECTION 16: Other information
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/