Phosphamidon SDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
- Product name： Phosphamidon
- CAS： 13171-21-6
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses： For R&D use only. Not for medicinal, household or other use.
- Uses advised against： none
Company Identification
- Company：Chemicalbook.in
- Address：5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
- Telephone：+91 9550333722
SECTION 2: Hazards identification
Classification of the substance or mixture
Acute toxicity - Category 2, Oral
Acute toxicity - Category 3, Dermal
Germ cell mutagenicity, Category 2
Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1
GHS label elements, including precautionary statements
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Pictogram(s)
- Signal word Danger
H300 Fatal if swallowed
H311 Toxic in contact with skin
H341 Suspected of causing genetic defects
H410 Very toxic to aquatic life with long lasting effects
P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P203 Obtain, read and follow all safety instructions before use.
P273 Avoid release to the environment.
P301+P316 IF SWALLOWED: Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P316 Get emergency medical help immediately.
P361+P364 Take off immediately all contaminated clothing and wash it before reuse.
P318 IF exposed or concerned, get medical advice.
P391 Collect spillage.
P405 Store locked up.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
Substance
- Chemical name: Phosphamidon
- Common names and synonyms: Phosphamidon
- CAS number: 13171-21-6
- EC number: 236-116-5
- Concentration: 100%
SECTION 4: First aid measures
Description of necessary first-aid measures
Fresh air, rest. Artificial respiration may be needed. Refer for medical attention.
Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention .
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Give a slurry of activated charcoal in water to drink. Refer immediately for medical attention. See Notes.
Most important symptoms/effects, acute and delayed
This material is extremely toxic; the probable oral lethal dose for humans is 5-50 mg/kg, or between 7 drops and 1 teaspoonful for a 150-lb person. It is a cholinesterase inhibitor. (EPA, 1998)
Indication of immediate medical attention and special treatment needed, if necessary
Airway protection. Insure that a clear airway exists. Intubate the patients and aspirate the secretions with a large-bore suction device if necessary. Administer oxygen by mechanically assisted pulmonary ventilation if respiration is depressed. Improve tissue oxygenation as much as possible before administering atropine, so as to minimize the risk of ventricular fibrillation. In severe poisonings, it may be necessary to support pulmonary ventilation mechanically for several days. Organophosphate pesticides
SECTION 5: Firefighting measures
Suitable extinguishing media
If material on fire or involved in fire: Do not extinguish fire unless flow can be stopped. Use water in flooding quantities as fog. Solid streams of water may be ineffective. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible. Use "alcohol" foam, dry chemical or carbon dioxide. Organophosphorus pesticides, liquid, flammable, toxic; Organophosphorus pesticides, liquid, toxic
Specific hazards arising from the chemical
Non-Specific -- Organophosphorus Pesticide, Liquid, n.o.s.) Container may explode in heat of fire. Heat above 320F may cause decomposition and evolution of highly toxic fumes of phosphorus oxides and chlorides. Hydrolyzes in alkali. Stable in neutral and acid media. Hydrolyzes in alkali. (EPA, 1998)
Special protective actions for fire-fighters
In case of fire in the surroundings, use appropriate extinguishing media.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Personal protection: chemical protection suit including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Collect leaking and spilled liquid in sealable non-metallic containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.
Environmental precautions
Personal protection: chemical protection suit including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Collect leaking and spilled liquid in sealable non-metallic containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.
Methods and materials for containment and cleaning up
Environmental considerations: Air spill: Apply water spray or mist to knock down vapors. Organophosphorus pesticides, liquid, flammable, toxic; Organophosphorus pesticides, liquid, toxic; Organophosphorus pesticides, solid, toxic
SECTION 7: Handling and storage
Precautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store in an area without drain or sewer access. Well closed. Keep in a well-ventilated room. Separated from bases and food and feedstuffs.You should store this material under ambient temperatures.
SECTION 8: Exposure controls/personal protection
Control parameters
no data available
no data available
Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures, such as personal protective equipment (PPE)
Wear face shield or eye protection in combination with breathing protection.
Protective gloves. Protective clothing.
Use ventilation, local exhaust or breathing protection.
no data available
SECTION 9: Physical and chemical properties and safety characteristics
-
Physical state：
Phosphamidon is a pale yellow oily liquid with a faint odor. Used as an insecticide for citrus, cotton, and deciduous fruit and nuts. and as an acaricide. (EPA, 1998)
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Colour：
Pale-yellow liquid
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Odour：
FAINT ODOR
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Melting point/freezing point：
-45°C
-
Boiling point or initial boiling point and boiling range：
160~162
-
Flammability：
Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire.
-
Lower and upper explosion limit/flammability limit：
no data available
-
Flash point：
169.1°C
-
Auto-ignition temperature：
no data available
-
Decomposition temperature：
no data available
-
pH：
no data available
-
Kinematic viscosity：
DENSITY: 1.22 @ 20 DEG C/4 DEG C; VISCOSITY: 70 CENTIPOISES @ 25 DEG C /TECHNICAL PRODUCT/
-
Solubility：
greater than or equal to 100 mg/mL at 72° F (NTP, 1992)
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Partition coefficient n-octanol/water：
0.8
-
Vapour pressure：
3E-05mmHg at 25°C
-
Density and/or relative density：
1.21
-
Relative vapour density：
no data available
-
Particle characteristics：
no data available
SECTION 10: Stability and reactivity
Reactivity
Decomposes on heating and on burning. This produces highly toxic fumes including phosphorus oxides, hydrogen chloride and nitrogen oxides. Reacts with bases (hydrolysis). Attacks metals such as iron, tin and aluminium.
Chemical stability
Isomeric mixt stable in neutral & acid media; half-life @ 23 deg c= 13.8 days @ ph 7, 2.2 days @ ph 10
Possibility of hazardous reactions
PHOSPHAMIDON is corrosive to iron, tin and aluminum. Incompatible with alkaline preparations and should not be mixed with copper oxychloride, captan, folpet or sulfur. (NTP, 1992)
Conditions to avoid
no data available
Incompatible materials
Reacts with bases (hydrolysis). Attacks metals such as iron, tin and aluminium.
Hazardous decomposition products
When heated to decomposition it emits toxic fumes of /phosphorous and nitric oxides/.
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 Rat oral 17.4 mg/kg
- Inhalation: LC50 Rat inhalation 135 mg/cu m/4 hr (whole body exposure)
- Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
Cancer Classification: Group C Possible Human Carcinogen
Reproductive toxicity
no data available
STOT-single exposure
The substance is irritating to the eyes. The substance may cause effects on the nervous system. This may result in convulsions, respiratory depression and death. Exposure at high levels could cause death. Cholinesterase inhibition. The effects may be delayed. Medical observation is indicated.
STOT-repeated exposure
Cholinesterase inhibition. Cumulative effects are possible. See Acute Hazards/Symptoms.
Aspiration hazard
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly on spraying.
SECTION 12: Ecological information
Toxicity
- Toxicity to fish: LC50 Pimephales promelas (fathead minnow) 100 mg/L/96 hr at 18 deg C, wt 1.0 g (95% confidence limit 91-110 mg/L). Static bioassay without aeration, pH 7.2-7.5, water hardness 40-50 mg/l as calcium carbonate and alkalinity of 30-35 mg/l. /Technical material, 80%
- Toxicity to daphnia and other aquatic invertebrates: no data available
- Toxicity to algae: no data available
- Toxicity to microorganisms: no data available
Persistence and degradability
AEROBIC: When applied at 5 ppm, the half-lives of phosphamidon in loam, loamy sand, and sand was approximately 6, 3, and <3 days, respectively(1,2). At an application rate of 1 ppm, the half-life in loam and silt was three to four weeks(1,2). No data on sterile controls were presented, and the pH of the soils studied were not reported.
Bioaccumulative potential
BCFs of <1 were measured for phosphamidon in zebrafish (Brachydanio rerio) using OECD test guideline 305 in a continuous flow-through system operated for 168 hrs with test concns of 995.4 and 198.3 ug/l(1). According to a classification scheme(2), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC). Bioconcentration of phosphamidon is unlikely due to its high water solubility(1), very low lipophilicity(1) and very rapid depuration(1,3).
Mobility in soil
The leaching behavior of phosphamidon in sand, loamy sand, loam, and silt soil in a 15 cm column was studied after 150 cm of rain applied(2). All the added phosphamidon leached through the sand and sandy loam soil, while most of the residue was in the lower third of the column(2). With the silt soil, residues were rather evenly distributed throughout the column and in the leachate, although the greatest fraction of residue was in the upper third of the column. In contrast with the good total recoveries in the other cases, recovery with the silt column was only 39%(2). According to a soil thin layer chromatography study with four soils, phosphamidon was very mobile (retardation factor (Rf) 0.91-0.92) in a silt loam (0.83% organic matter, pH 7.9), silt loam (0.72% organic matter, pH 6.6), and a fine sandy loam (0.52% organic matter, pH 8.8)(1). It was less mobile (Rf = 0.66) in a sandy loam (0.69% organic matter, pH 10.5)(1).
Other adverse effects
no data available
SECTION 13: Disposal considerations
Disposal methods
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
UN Number
ADR/RID: UN3018 (For reference only, please check.)
IMDG: UN3018 (For reference only, please check.)
IATA: UN3018 (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: ORGANOPHOSPHORUS PESTICIDE, LIQUID, TOXIC (For reference only, please check.)
IMDG: ORGANOPHOSPHORUS PESTICIDE, LIQUID, TOXIC (For reference only, please check.)
IATA: ORGANOPHOSPHORUS PESTICIDE, LIQUID, TOXIC (For reference only, please check.)
Transport hazard class(es)
ADR/RID: 6.1 (For reference only, please check.)
IMDG: 6.1 (For reference only, please check.)
IATA: 6.1 (For reference only, please check.)
Packing group, if applicable
ADR/RID: I (For reference only, please check.)
IMDG: I (For reference only, please check.)
IATA: I (For reference only, please check.)
Environmental hazards
ADR/RID: Yes
IMDG: Yes
IATA: Yes
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
Safety, health and environmental regulations specific for the product in question
SECTION 16: Other information
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Other Information
Depending on the degree of exposure, periodic medical examination is suggested.Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.Commercial product is a mixture of isomers.Carrier solvents used in commercial formulations may change physical and toxicological properties.Do NOT take working clothes home.