Osmium tetraoxide SDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
- Product name： Osmium tetraoxide
- CAS： 20816-12-0
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses： For R&D use only. Not for medicinal, household or other use.
- Uses advised against： none
Company Identification
- Company：Chemicalbook.in
- Address：5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
- Telephone：+91 9550333722
SECTION 2: Hazards identification
Classification of the substance or mixture
Acute toxicity - Category 2, Oral
Acute toxicity - Category 1, Dermal
Skin corrosion, Sub-category 1B
Acute toxicity - Category 2, Inhalation
GHS label elements, including precautionary statements
-
Pictogram(s)
- Signal word Danger
H300 Fatal if swallowed
H310 Fatal in contact with skin
H314 Causes severe skin burns and eye damage
H330 Fatal if inhaled
P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P262 Do not get in eyes, on skin, or on clothing.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P284 [In case of inadequate ventilation] wear respiratory protection.
P301+P316 IF SWALLOWED: Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P316 Get emergency medical help immediately.
P361+P364 Take off immediately all contaminated clothing and wash it before reuse.
P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P363 Wash contaminated clothing before reuse.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P320 Specific treatment is urgent (see ... on this label).
P405 Store locked up.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
Substance
- Chemical name: Osmium tetraoxide
- Common names and synonyms: Osmium tetraoxide
- CAS number: 20816-12-0
- EC number: 244-058-7
- Concentration: 100%
SECTION 4: First aid measures
Description of necessary first-aid measures
Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention.
First rinse with plenty of water for at least 15 minutes, then remove contaminated clothes and rinse again. Refer for medical attention .
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Rinse mouth. Give nothing to drink. Rest. Refer for medical attention .
Most important symptoms/effects, acute and delayed
Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]: TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution. (ERG, 2016)
Indication of immediate medical attention and special treatment needed, if necessary
Basic treatment: Establish a patent airway. Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if needed. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary . Monitor for shock and treat if necessary . Anticipate seizures and treat if necessary . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool . Cover skin burns with dry sterile dressings after decontamination . Poison A and B
SECTION 5: Firefighting measures
Suitable extinguishing media
If material on fire or involved in fire: Extinguish fire using agent suitable for type of surrounding fire. (Material itself does not burn or burns with difficulty.) Use water in flooding quantities as fog. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible. Solid streams of water may spread the fire.
Specific hazards arising from the chemical
Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]: Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Some are oxidizers and may ignite combustibles (wood, paper, oil, clothing, etc.). Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. For electric vehicles or equipment, ERG Guide 147 (lithium ion batteries) or ERG Guide 138 (sodium batteries) should also be consulted. (ERG, 2016)
Special protective actions for fire-fighters
In case of fire in the surroundings, use appropriate extinguishing media.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Evacuate danger area! Consult an expert! Personal protection: complete protective clothing including self-contained breathing apparatus. Ventilation. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Then store and dispose of according to local regulations. Do NOT absorb in saw-dust or other combustible absorbents.
Environmental precautions
Evacuate danger area! Consult an expert! Personal protection: complete protective clothing including self-contained breathing apparatus. Ventilation. Do NOT let this chemical enter the environment. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Then store and dispose of according to local regulations. Do NOT absorb in saw-dust or other combustible absorbents.
Methods and materials for containment and cleaning up
Ventilate area of spill or leak. Collect material liquid containing osmium tetroxide should be absorbed in vermiculite, dry sand, earth, or a similar material.
SECTION 7: Handling and storage
Precautions for safe handling
NO contact with flammables. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Separated from combustible substances, reducing agents and food and feedstuffs. Ventilation along the floor.Separated from combustible and reducing substances, food and feedstuffs. Ventilation along the floor.
SECTION 8: Exposure controls/personal protection
Control parameters
TLV: 0.0002 ppm as TWA; 0.0006 ppm as STEL
no data available
Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures, such as personal protective equipment (PPE)
Wear safety goggles or eye protection in combination with breathing protection if powder.
Protective gloves. Protective clothing.
Use local exhaust or breathing protection.
no data available
SECTION 9: Physical and chemical properties and safety characteristics
-
Physical state：
Osmium tetroxide is a colorless or yellow solid with a pungent odor of chlorine. Begins to sublime below melting point. Soluble in alcohol. Toxic by inhalation and a strong irritant to the eyes and mucous membranes.
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Colour：
Pale yellow solid; monoclinic crystals
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Odour：
Acrid, chlorine-like odor
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Melting point/freezing point：
40°C
-
Boiling point or initial boiling point and boiling range：
130°C(lit.)
-
Flammability：
Noncombustible Solid
-
Lower and upper explosion limit/flammability limit：
no data available
-
Flash point：
4°C
-
Auto-ignition temperature：
no data available
-
Decomposition temperature：
no data available
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pH：
no data available
-
Kinematic viscosity：
no data available
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Solubility：
6 % at 77° F (NIOSH, 2016)
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Partition coefficient n-octanol/water：
no data available
-
Vapour pressure：
7 mm Hg (NIOSH, 2016)
-
Density and/or relative density：
1.0g/mLat 20°C
-
Relative vapour density：
8.8 (vs air)
-
Particle characteristics：
no data available
SECTION 10: Stability and reactivity
Reactivity
Decomposes on heating. This produces fumes of osmium. The substance is a strong oxidant. It reacts with combustible and reducing materials. Reacts with hydrochloric acid. This produces toxic gas (chlorine - see ICSC 0126). Mixtures with alkalis are unstable.
Chemical stability
Readily vaporizes from aqueous solution even at room temperature
Possibility of hazardous reactions
Not combustible.OSMIUM TETROXIDE is incompatible with hydrochloric acid and easily oxidizes organic materials. Contact with other materials may cause fire. (NIOSH, 2016). Reacts explosively with 1-methylimidazole [J. Chem. Soc., Dalton Trans., 1979, 1084].
Conditions to avoid
no data available
Incompatible materials
Contact with hydrochloric acid will cause formation of poisonous chlorine gas. Contact with easily oxidized organic materials may cause fires and explosions.
Hazardous decomposition products
When heated to decomposition, it emits toxic fumes of /osmium/.
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 Mouse oral 162 mg/kg
- Inhalation: no data available
- Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
no data available
Reproductive toxicity
no data available
STOT-single exposure
Lachrymation. The substance is corrosive to the eyes, skin and respiratory tract. Inhalation may cause lung oedema. See Notes. Exposure to high concentrations could cause death. The effects may be delayed. Medical observation is indicated.
STOT-repeated exposure
Repeated or prolonged contact with skin may cause dermatitis. The substance may have effects on the kidneys.
Aspiration hazard
A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20°C.
SECTION 12: Ecological information
Toxicity
- Toxicity to fish: no data available
- Toxicity to daphnia and other aquatic invertebrates: no data available
- Toxicity to algae: no data available
- Toxicity to microorganisms: no data available
Persistence and degradability
no data available
Bioaccumulative potential
no data available
Mobility in soil
no data available
Other adverse effects
no data available
SECTION 13: Disposal considerations
Disposal methods
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
UN Number
ADR/RID: UN2471 (For reference only, please check.)
IMDG: UN2471 (For reference only, please check.)
IATA: UN2471 (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: OSMIUM TETROXIDE (For reference only, please check.)
IMDG: OSMIUM TETROXIDE (For reference only, please check.)
IATA: OSMIUM TETROXIDE (For reference only, please check.)
Transport hazard class(es)
ADR/RID: 6.1 (For reference only, please check.)
IMDG: 6.1 (For reference only, please check.)
IATA: 6.1 (For reference only, please check.)
Packing group, if applicable
ADR/RID: I (For reference only, please check.)
IMDG: I (For reference only, please check.)
IATA: I (For reference only, please check.)
Environmental hazards
ADR/RID: No
IMDG: No
IATA: No
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
Safety, health and environmental regulations specific for the product in question
SECTION 16: Other information
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Other Information
Begins to sublime and distil well below boiling point.The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential.Immediate administration of an appropriate spray, by a doctor or a person authorized by him/her, should be considered.The odour warning when the exposure limit value is exceeded is insufficient.Do NOT take working clothes home.Rinse contaminated clothing with plenty of water because of fire hazard.