Monocrotophos SDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
- Product name： Monocrotophos
- CAS： 6923-22-4
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses： For R&D use only. Not for medicinal, household or other use.
- Uses advised against： none
Company Identification
- Company：Chemicalbook.in
- Address：5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
- Telephone：+91 9550333722
SECTION 2: Hazards identification
Classification of the substance or mixture
Acute toxicity - Category 2, Oral
Acute toxicity - Category 3, Dermal
Acute toxicity - Category 2, Inhalation
Germ cell mutagenicity, Category 2
Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1
GHS label elements, including precautionary statements
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Pictogram(s)
- Signal word Danger
H300 Fatal if swallowed
H311 Toxic in contact with skin
H330 Fatal if inhaled
H341 Suspected of causing genetic defects
H410 Very toxic to aquatic life with long lasting effects
P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P284 [In case of inadequate ventilation] wear respiratory protection.
P203 Obtain, read and follow all safety instructions before use.
P273 Avoid release to the environment.
P301+P316 IF SWALLOWED: Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P316 Get emergency medical help immediately.
P361+P364 Take off immediately all contaminated clothing and wash it before reuse.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P320 Specific treatment is urgent (see ... on this label).
P318 IF exposed or concerned, get medical advice.
P391 Collect spillage.
P405 Store locked up.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
Substance
- Chemical name: Monocrotophos
- Common names and synonyms: Monocrotophos
- CAS number: 6923-22-4
- EC number: 230-042-7
- Concentration: 100%
SECTION 4: First aid measures
Description of necessary first-aid measures
Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer immediately for medical attention.
Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer immediately for medical attention. Wear protective gloves when administering first aid.
Rinse with plenty of water (remove contact lenses if easily possible). Refer immediately for medical attention.
Rinse mouth. Give a slurry of activated charcoal in water to drink. Do NOT induce vomiting. Refer immediately for medical attention. See Notes.
Most important symptoms/effects, acute and delayed
Monocrotophos is an organophosphorus pesticide. It is a cholinesterase inhibitor and acts on the nervous system. Extremely toxic; probable oral lethal dose to humans 5-50 mg/kg or between 7 drops and 1 teaspoon for a 70 kg (150 lb.) person. Repeated inhalation or skin contact with this material may, without symptoms, progressively increase susceptibility to poisoning. (EPA, 1998)
Indication of immediate medical attention and special treatment needed, if necessary
Antidote: Atropine combined with oxime preparation, e.g. PAM or Toxogonin. Atropine is the emergency antidote for Azodrin poisoning. 2-PAM is also antidotal and may be used in conjunction with atropine. Do not use morphine.
SECTION 5: Firefighting measures
Suitable extinguishing media
Use water, foam, carbon dioxide, or dry chemical to extinguish fires. Malathion
Specific hazards arising from the chemical
Wear positive pressure breathing apparatus and full protective clothing. Container may explode in heat of fire. Toxic fumes evolved when heated to decomposition. Incompatible with alkaline compounds. Unstable in aqueous solution above pH 7.0; in low molecular weight alcohols and glycols. Stable in ketones and higher molecular weight alcohols and glycols. Stable when stored in glass or polyethylene containers. Relatively stable in sunlight. Keep away from temperatures above 80F; do not store below 70F. Corrosive to black iron, drum steel, stainless steel 304 and brass, but not to glass, aluminum, or stainless steel 316. (EPA, 1998)
Special protective actions for fire-fighters
Use water spray, dry powder, foam, carbon dioxide.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Personal protection: complete protective clothing including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Sweep spilled substance into covered sealable, plastic containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.
Environmental precautions
Personal protection: complete protective clothing including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Sweep spilled substance into covered sealable, plastic containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.
Methods and materials for containment and cleaning up
Spills of malathion on floors shall be absorbed with absorbing clay. Sweeping compound may be utilized to facilitate the removal of all visible traces of malathion contaminated clay. Equipment and fixtures contaminated with malathion shall be decontaminated with an alkaline solution (5% sodium hydroxide). Malathion
SECTION 7: Handling and storage
Precautions for safe handling
NO open flames. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs. Dry. Well closed. Keep in a well-ventilated room. Store in an area without drain or sewer access.DO NOT STORE /AZODRIN 5/ BELOW 70 DEG F OR ABOVE 80 DEG F FOR PROLONGED PERIODS. AZODRIN 5 IS EXTREMELY FLAMMABLE.
SECTION 8: Exposure controls/personal protection
Control parameters
TLV: 0.05 mg/m3, as TWA; (skin); A4 (not classifiable as a human carcinogen); BEI issued
no data available
Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures, such as personal protective equipment (PPE)
Wear face shield or eye protection in combination with breathing protection if powder.
Protective gloves. Protective clothing.
Use ventilation (not if powder), local exhaust or breathing protection.
no data available
SECTION 9: Physical and chemical properties and safety characteristics
-
Physical state：
Monocrotophos is a colorless crystals with a mild ester odor, commercial product is a reddish-brown solid. Used as a fast acting insecticide with both systemic and contact action against a wide range of pests on cotton, sugar cane, tobacco, potatoes, peanuts, tomatoes, and ornamentals. Very toxic.
-
Colour：
Reddish brown solid
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Odour：
Mild, ester odor.
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Melting point/freezing point：
54-55°C
-
Boiling point or initial boiling point and boiling range：
125°C (0.0005 torr)
-
Flammability：
Combustible Solid
-
Lower and upper explosion limit/flammability limit：
no data available
-
Flash point：
2°C
-
Auto-ignition temperature：
no data available
-
Decomposition temperature：
no data available
-
pH：
no data available
-
Kinematic viscosity：
no data available
-
Solubility：
Miscible (NIOSH, 2016)
-
Partition coefficient n-octanol/water：
log Kow = -0.20
-
Vapour pressure：
7e-06 mm Hg at 68° F (EPA, 1998)
-
Density and/or relative density：
1.195g/cm3
-
Relative vapour density：
no data available
-
Particle characteristics：
no data available
SECTION 10: Stability and reactivity
Reactivity
Decomposes on heating and on burning. This produces toxic and irritating fumes including nitrogen oxides and phosphorus oxides. Attacks iron, steel and brass.
Chemical stability
On hydrolysis @ 20 deg C, the calculated half-life at pH 5 = 96 days, at pH 7 = 66 days, and at pH 9 = 17 days.
Possibility of hazardous reactions
AZODRIN 5 IS EXTREMELY FLAMMABLE.MONOCROTOPHOS is incompatible with the following: Metals, low molecular weight alcohols & glycols [Note: Corrosive to black iron, drum steel, stainless steel 304 & brass. Should be stored at 70-80°F.] (NIOSH, 2016). Incompatible with alkaline compounds.
Conditions to avoid
no data available
Incompatible materials
Incompatible with /pesticides/ which are alkaline in reaction.
Hazardous decomposition products
When heated to decomposition it emits very toxic fumes.
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 Rat oral 21 mg/kg
- Inhalation: LC50 rat inhalation (4 hr) = circa 0.08 mg/L
- Dermal: LD50 Rabbit percutaneous 112-709 mg/kg
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
A4; Not classifiable as a human carcinogen.
Reproductive toxicity
no data available
STOT-single exposure
Cholinesterase inhibition. The substance may cause effects on the nervous system. This may result in convulsions and respiratory failure. Medical observation is indicated. Exposure could cause death. The effects may be delayed. See Notes.
STOT-repeated exposure
Cholinesterase inhibition. Cumulative effects are possible. See Acute Hazards/Symptoms.
Aspiration hazard
A harmful concentration of airborne particles can be reached quickly when dispersed.
SECTION 12: Ecological information
Toxicity
- Toxicity to fish: LC50 Bluegill 12.1 mg/l/96 hr (95% confidence limit 7.2-10.1 mg/l) /as stated in source/, wt 1.0 g. Static bioassay without aeration, pH 7.2-7.5, water hardness 40-50 mg/l as calcium carbonate and alkalinity of 30-35 mg/l. /Technical material, 100%
- Toxicity to daphnia and other aquatic invertebrates: no data available
- Toxicity to algae: no data available
- Toxicity to microorganisms: no data available
Persistence and degradability
The soil algae, Chlorella vulgaris, Scenedesmus bijugatus, Synechococcus elongatus, Phormidium tenue, and Nostoc linckia, began metabolizing monocrotophos following 10 days of incubation(1). Monocrotophos is rapidly degraded in soil with half-lives ranging from 1 to 5 days(2). The half-life of azodrin in culture solution was 4.6 days(3). 100% of monocrotophos persisted after eight weeks incubation in raw river water(4).
Bioaccumulative potential
An estimated BCF value of 0.41 was calculated for monocrotophos(SRC), using an estimated log Kow of -0.20(1,SRC) and a recommended regression-derived equation(2). According to a classification scheme(3), this BCF value suggests that bioconcentration in aquatic organisms is low(SRC).
Mobility in soil
The Koc of monocrotophos is estimated as approximately 19(SRC), using a measured log Kow of -0.20(1) and a regression-derived equation(2,SRC). According to a recommended classification scheme(3), this estimated Koc value suggests that monocrotophos is expected to have very high mobility in soil(SRC).
Other adverse effects
no data available
SECTION 13: Disposal considerations
Disposal methods
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
UN Number
ADR/RID: UN2783 (For reference only, please check.)
IMDG: UN2783 (For reference only, please check.)
IATA: UN2783 (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: ORGANOPHOSPHORUS PESTICIDE, SOLID, TOXIC (For reference only, please check.)
IMDG: ORGANOPHOSPHORUS PESTICIDE, SOLID, TOXIC (For reference only, please check.)
IATA: ORGANOPHOSPHORUS PESTICIDE, SOLID, TOXIC (For reference only, please check.)
Transport hazard class(es)
ADR/RID: 6.1 (For reference only, please check.)
IMDG: 6.1 (For reference only, please check.)
IATA: 6.1 (For reference only, please check.)
Packing group, if applicable
ADR/RID: I (For reference only, please check.)
IMDG: I (For reference only, please check.)
IATA: I (For reference only, please check.)
Environmental hazards
ADR/RID: Yes
IMDG: Yes
IATA: Yes
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
Safety, health and environmental regulations specific for the product in question
SECTION 16: Other information
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Other Information
This card applies to trans-monocrotophos.Depending on the degree of exposure, periodic medical examination is suggested.Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.If the substance is formulated with solvents also consult the ICSCs of these materials.Carrier solvents used in commercial formulations may change physical and toxicological properties.Do NOT take working clothes home.CAS 919-44-8 is cis-monocrotophos, and CAS 2157-98-4 is unspecified monocrotophos.