Methyl acetate SDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
- Product name： Methyl acetate
- CAS： 79-20-9
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses： For R&D use only. Not for medicinal, household or other use.
- Uses advised against： none
Company Identification
- Company：Chemicalbook.in
- Address：5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
- Telephone：+91 9550333722
SECTION 2: Hazards identification
Classification of the substance or mixture
Flammable liquids, Category 2
Eye irritation, Category 2
Specific target organ toxicity – single exposure, Category 3
GHS label elements, including precautionary statements
-
Pictogram(s)
- Signal word Danger
H225 Highly flammable liquid and vapour
H319 Causes serious eye irritation
H336 May cause drowsiness or dizziness
P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P233 Keep container tightly closed.
P240 Ground and bond container and receiving equipment.
P241 Use explosion-proof [electrical/ventilating/lighting/...] equipment.
P242 Use non-sparking tools.
P243 Take action to prevent static discharges.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P264 Wash ... thoroughly after handling.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P303+P361+P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse affected areas with water [or shower].
P370+P378 In case of fire: Use ... to extinguish.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P319 Get medical help if you feel unwell.
P403+P235 Store in a well-ventilated place. Keep cool.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
Substance
- Chemical name: Methyl acetate
- Common names and synonyms: Methyl acetate
- CAS number: 79-20-9
- EC number: 201-185-2
- Concentration: 100%
SECTION 4: First aid measures
Description of necessary first-aid measures
Fresh air, rest. Refer for medical attention.
Rinse contaminated clothes (fire hazard) with plenty of water. Remove contaminated clothes. Rinse skin with plenty of water or shower.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Rinse mouth. Give one or two glasses of water to drink. Refer for medical attention .
Most important symptoms/effects, acute and delayed
Very similar to those of methyl alcohol, which constitutes 20% of commercial grade.) Inhalation causes headache, fatigue, and drowsiness; high concentrations can produce central nervous system depression and optic nerve damage. Liquid irritates eyes and may cause defatting and cracking of skin. Ingestion causes headache, dizziness, drowsiness, fatigue; may cause severe eye damage. (USCG, 1999)
Indication of immediate medical attention and special treatment needed, if necessary
Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand-valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR as necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. Methyl alcohol and related compounds
SECTION 5: Firefighting measures
Suitable extinguishing media
Suitable extinguishing media: Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Specific hazards arising from the chemical
Behavior in Fire: Vapor is heavier than air and may travel a considerable distance to a source of ignition and flash back. (USCG, 1999)
Special protective actions for fire-fighters
Use alcohol-resistant foam, foam, powder, carbon dioxide, fine water spray. In case of fire: keep drums, etc., cool by spraying with water.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Remove all ignition sources. Evacuate danger area! Consult an expert! Personal protection: filter respirator for organic gases and vapours of low boiling point adapted to the airborne concentration of the substance. Do NOT wash away into sewer. Collect leaking liquid in sealable containers. Absorb liquid in sand or inert absorbent. Then store and dispose of according to local regulations.
Environmental precautions
Remove all ignition sources. Evacuate danger area! Consult an expert! Personal protection: filter respirator for organic gases and vapours of low boiling point adapted to the airborne concentration of the substance. Do NOT wash away into sewer. Collect leaking liquid in sealable containers. Absorb liquid in sand or inert absorbent. Then store and dispose of according to local regulations.
Methods and materials for containment and cleaning up
Remove all ignition sources. Establish forced ventilation to keep levels below explosive limit. Absorb liquids in vermiculite, dry sand, earth, peat, carbon or a similar materail and deposit in sealed containers. Keep this chemical out of a confined space, such as a sewer, because of the possibility of an explosion.
SECTION 7: Handling and storage
Precautions for safe handling
NO open flames, NO sparks and NO smoking. Closed system, ventilation, explosion-proof electrical equipment and lighting. Use non-sparking handtools. Do NOT use compressed air for filling, discharging, or handling. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Fireproof. Separated from strong oxidants, strong acids and strong bases.Store in a flammable liquid storage area or approved cabinet away from ignition sources and corrosive and reactive materials. ... Methyl acetate must be stored to avoid contact with strong oxidizers (such as chlorine, bromine, and fluorine) and strong acids (such as hydrochloric, sulfuric, and nitric), since violent reactions occur. Store in tightly closed containers in a cool, well-ventilated area away from strong alkalis and nitrates. Sources of ignition, such as smoking and open flames, are prohibited where methyl acetate is used, handled or stored in a manner that could create a potential fire or explosion hazard. Use only nonsparking tools and equipment, especially when opening and closing containers of methyl acetate.
SECTION 8: Exposure controls/personal protection
Control parameters
TLV: 200 ppm as TWA; 250 ppm as STEL.MAK: 310 mg/m3, 100 ppm; peak limitation category: I(4); pregnancy risk group: C
no data available
Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures, such as personal protective equipment (PPE)
Wear safety goggles or eye protection in combination with breathing protection.
Protective gloves.
Use ventilation, local exhaust or breathing protection.
no data available
SECTION 9: Physical and chemical properties and safety characteristics
-
Physical state：
Methyl acetate is a clear colorless liquid with a fragrant odor. Moderately toxic. Flash point 14°F. Vapors heavier than air.
-
Colour：
Colorless, volatile liquid
-
Odour：
Pleasant odor
-
Melting point/freezing point：
19°C(lit.)
-
Boiling point or initial boiling point and boiling range：
57-58°C(lit.)
-
Flammability：
Class IB Flammable Liquid: Fl.P. below 73°F and BP at or above 100°F.
-
Lower and upper explosion limit/flammability limit：
Lower flammable limit: 3.1% by volume; Upper flammable limit: 16% by volume
-
Flash point：
-13°C
-
Auto-ignition temperature：
936°F
-
Decomposition temperature：
no data available
-
pH：
no data available
-
Kinematic viscosity：
0.364 mPa.s at 25 deg C
-
Solubility：
greater than or equal to 100 mg/mL at 70° F (NTP, 1992)
-
Partition coefficient n-octanol/water：
log Kow = 0.18
-
Vapour pressure：
170 mm Hg at 68° F ; 235 mm Hg at 77° F (NTP, 1992)
-
Density and/or relative density：
0.934g/mLat 25°C
-
Relative vapour density：
2.55 (vs air)
-
Particle characteristics：
no data available
SECTION 10: Stability and reactivity
Reactivity
3100 ppm (IDLH based on 10% of the lower explosive limit for safety considerations even though the relevant toxicological data indicated that irreversible health effects or impairment of escape existed only at higher concentrations.)
It reacts with strong oxidants. This generates fire or explosion hazard. It reacts violently with strong acids and strong bases. Attacks rubber and some forms of plastic.
Chemical stability
Stable under recommended storage conditions.
Possibility of hazardous reactions
Dangerous fire hazard when exposed to heat, flame, or oxidizers.The vapour is heavier than air and may travel along the ground; distant ignition possible.METHYL ACETATE presents a fire or explosion hazard when exposed to strong oxidizing agents. Emits irritating fumes and acrid smoke when heated to decomposition, [Lewis, 3rd ed., 1993, p. 826]. Its reactivity is consistent with other compounds of the ester group.
Conditions to avoid
no data available
Incompatible materials
Forms explosive mixture with air. a strong reducing agent. Incompatible with water, acids, nitrates, strong oxidizers, alkalis. Attacks some plastics. Attacks many metals in teh presence of water. Reacts slowly with water, forming acetic acid and methanol.
Hazardous decomposition products
Decomposes in heat; on contact with air, bases, strong oxidizers, UV-light, casuing fire and explosion hazard.
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 Rat oral 6,482 mg/kg
- Inhalation: LC50 Cat inhalation > 30 mg/L 10hr
- Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
no data available
Reproductive toxicity
no data available
STOT-single exposure
The substance is irritating to the eyes and respiratory tract. The substance is mildly irritating to the skin. The substance may cause effects on nervous system. Exposure far above the OEL could cause lowering of consciousness.
STOT-repeated exposure
The substance defats the skin, which may cause dryness or cracking. The substance may have effects on the optic nerve. This may result in impaired vision.
Aspiration hazard
A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C.
SECTION 12: Ecological information
Toxicity
- Toxicity to fish: LC50; Species: Pimephales promelas (fathead minnows); Concentration: 399 mg/L for 96 hr (confidence limit 378-422 mg/L) /Conditions of bioassay not specified
- Toxicity to daphnia and other aquatic invertebrates: no data available
- Toxicity to algae: no data available
- Toxicity to microorganisms: no data available
Persistence and degradability
AEROBIC: Methyl acetate achieved >70% after 28 days in an OECD 301D Closed bottle test(1). Methyl acetate reached > 95% degradation in a 5 day BOD test(2).
Bioaccumulative potential
An estimated BCF of 3.2 was calculated in fish for methyl acetate(SRC), using a log Kow of 0.18(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).
Mobility in soil
The Koc of methyl acetate is estimated as 9.1(SRC), using a log Kow of 0.18(1) and a regression-derived equation(2). According to a classification scheme(3), this estimated Koc value suggests that methyl acetate is expected to have very high mobility in soil(SRC).
Other adverse effects
no data available
SECTION 13: Disposal considerations
Disposal methods
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
UN Number
ADR/RID: UN1231 (For reference only, please check.)
IMDG: UN1231 (For reference only, please check.)
IATA: UN1231 (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: METHYL ACETATE (For reference only, please check.)
IMDG: METHYL ACETATE (For reference only, please check.)
IATA: METHYL ACETATE (For reference only, please check.)
Transport hazard class(es)
ADR/RID: 3 (For reference only, please check.)
IMDG: 3 (For reference only, please check.)
IATA: 3 (For reference only, please check.)
Packing group, if applicable
ADR/RID: II (For reference only, please check.)
IMDG: II (For reference only, please check.)
IATA: II (For reference only, please check.)
Environmental hazards
ADR/RID: No
IMDG: No
IATA: No
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
Safety, health and environmental regulations specific for the product in question
SECTION 16: Other information
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Other Information
Do NOT take working clothes home.The odour warning when the exposure limit value is exceeded is insufficient.