Methomyl SDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
- Product name： Methomyl
- CAS： 16752-77-5
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses： For R&D use only. Not for medicinal, household or other use.
- Uses advised against： none
Company Identification
- Company：Chemicalbook.in
- Address：5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
- Telephone：+91 9550333722
SECTION 2: Hazards identification
Classification of the substance or mixture
Acute toxicity - Category 2, Oral
Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1
GHS label elements, including precautionary statements
-
Pictogram(s)
- Signal word Danger
H300 Fatal if swallowed
H410 Very toxic to aquatic life with long lasting effects
P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P273 Avoid release to the environment.
P301+P316 IF SWALLOWED: Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P330 Rinse mouth.
P391 Collect spillage.
P405 Store locked up.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
Substance
- Chemical name: Methomyl
- Common names and synonyms: Methomyl
- CAS number: 16752-77-5
- EC number: 240-815-0
- Concentration: 100%
SECTION 4: First aid measures
Description of necessary first-aid measures
Fresh air, rest. Half-upright position. Refer for medical attention. See Notes.
Remove contaminated clothes. Rinse skin with plenty of water or shower.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Give a slurry of activated charcoal in water to drink. Refer immediately for medical attention.
Most important symptoms/effects, acute and delayed
Methomyl has high oral toxicity, moderate inhalation toxicity and low skin toxicity. The probable oral lethal dose for humans is between 7 drops and 1 teaspoon for a 150 pound adult. Death is due to respiratory arrest. (EPA, 1998)
Indication of immediate medical attention and special treatment needed, if necessary
Basic treatment: Establish a patent airway. Suction if necessary. Aggressive airway control may be needed. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary . Monitor for shock and treat if necessary . Anticipate seizures and treat if necessary . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool. Administer activated charcoal . Carbamates and related compounds
SECTION 5: Firefighting measures
Suitable extinguishing media
Non-Specific -- Carbamate Pesticide, Solid) Wear self-contained breathing apparatus. (Non-Specific -- Carbamate Pesticide, Solid) Use agent suitable for type of surrounding fire. Use water in flooding quantities as a fog. Use alcohol foam, carbon dioxide, or dry chemical. (EPA, 1998)
Specific hazards arising from the chemical
When heated to decomposition, it emits very toxic fumes of nitrogen oxides and sulfur oxides. Do not subject liquid formulations to temperatures below 32F. (EPA, 1998)
Special protective actions for fire-fighters
Use water spray, foam, powder, carbon dioxide.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered sealable containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.
Environmental precautions
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered sealable containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.
Methods and materials for containment and cleaning up
A system for removing pesticides from the wash water produced by pesticide applicators as they clean their equipment has been developed. The first step is the flocculation/coagulation and sedimentation of the pesticide-contaminated wash water. The supernatant from the first step is then passed through activated carbon columns. Pesticides
SECTION 7: Handling and storage
Precautions for safe handling
NO open flames. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store in an area without drain or sewer access. Dry. Keep in a well-ventilated room. Separated from strong bases and food and feedstuffs.Keep /liq formulations/ away from heat, sparks, & open flame. Do not subject liquid to temperatures below 32 deg F.
SECTION 8: Exposure controls/personal protection
Control parameters
TLV: 0.2 mg/m3, as TWA; (skin); A4 (not classifiable as a human carcinogen); BEI issued
no data available
Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures, such as personal protective equipment (PPE)
Wear safety goggles or eye protection in combination with breathing protection.
Protective gloves.
Use local exhaust or breathing protection.
no data available
SECTION 9: Physical and chemical properties and safety characteristics
-
Physical state：
Methomyl is a white crystalline solid with slight sulfurous smell. Used as a nematocide, and an insecticide on vegetables, tobacco, cotton, alfalfa, soy beans, and corn. (EPA, 1998)
-
Colour：
White crystalline solid
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Odour：
Slightly sulfurous
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Melting point/freezing point：
78°C
-
Boiling point or initial boiling point and boiling range：
144°C
-
Flammability：
Noncombustible Solid, but may be dissolved in flammable liquids.
-
Lower and upper explosion limit/flammability limit：
no data available
-
Flash point：
no data available
-
Auto-ignition temperature：
no data available
-
Decomposition temperature：
no data available
-
pH：
no data available
-
Kinematic viscosity：
no data available
-
Solubility：
6 % at 77° F (NIOSH, 2016)
-
Partition coefficient n-octanol/water：
log Kow= 0.60
-
Vapour pressure：
5e-05 mm Hg at 77° F (EPA, 1998)
-
Density and/or relative density：
1.17 g/cm3
-
Relative vapour density：
no data available
-
Particle characteristics：
no data available
SECTION 10: Stability and reactivity
Reactivity
Decomposes on heating and on burning. This produces toxic and corrosive fumes including nitrogen oxides, sulfur oxides, hydrogen cyanide and methylisocyanate. Reacts with strong bases.
Chemical stability
Stable in neutral or slightly acidic soln.
Possibility of hazardous reactions
Liquid formulations flammable.METHOMYL is a carbamate ester. Carbamates are chemically similar to, but more reactive than amides. Like amides they form polymers such as polyurethane resins. Carbamates are incompatible with strong acids and bases, and especially incompatible with strong reducing agents such as hydrides. Flammable gaseous hydrogen is produced by the combination of active metals or nitrides with carbamates. Strongly oxidizing acids, peroxides, and hydroperoxides are incompatible with carbamates.
Conditions to avoid
no data available
Incompatible materials
Strong bases.
Hazardous decomposition products
When heated to decomposition it emits very toxic fumes of /nitrogen oxides & sulfur oxides/.
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 Rat (male) oral 17 mg active ingredient/kg
- Inhalation: LD50 Rat (male) inhalation 0.45 mg/kg/4 hr
- Dermal: LD50 Rabbit (male) percutaneous >5000 mg ai/kg
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
Cancer Classification: Group E Evidence of Non-carcinogenicity for Humans
Reproductive toxicity
no data available
STOT-single exposure
The substance is irritating to the eyes. The substance may cause effects on the nervous system. This may result in convulsions and respiratory depression. Cholinesterase inhibition. Exposure far above the OEL could cause death.
STOT-repeated exposure
The substance may have effects on the blood. This may result in anaemia.
Aspiration hazard
A harmful contamination of the air will not or will only very slowly be reached on evaporation of this substance at 20°C; on spraying or dispersing, however, much faster.
SECTION 12: Ecological information
Toxicity
- Toxicity to fish: LC50 Pimephales promelas (fathead minnow) 2.11 mg/l/96 at 24.1 deg C, 6.6 mg/l dissolved oxygen, 50.5 mg/l CaCO3 water hardness, 38.4 mg/l CaCO3 alkalinity, pH 7.4, tank vol 1.2 l, tank additions 12 vol/day, (95% confidence limit 1.84-2.42 mg/l), flow-through bioassay, purity, 99%
- Toxicity to daphnia and other aquatic invertebrates: no data available
- Toxicity to algae: no data available
- Toxicity to microorganisms: no data available
Persistence and degradability
Methomyl seemed to be stable for about 16 days after application to an alluvial soil, but then degraded faster in the non-autoclaved alluvial soil as compared to autoclaved soil suggesting the importance of microbial degradation(1). Soil microorganisms were found to be the primary factor responsible for methomyl conversion in various soil types(2). Laboratory studies indicated that methyl radiolabeled methomyl was rapidly degraded in soil via microbial action with carbon dioxide as the principal end product(3). Microbial transformation of methomyl in two tobacco-growing soils was found to occur after an initial lag phase of 7-14 days, but occurred with virtually no lag phase in soils previously treated with methomyl(4). After the initial lag phase, half-lives of about 5-6 weeks were determined for methomyl in these soils(4). Comparison with tests using soils sterilized with sodium azide suggested that microbial transformation is likely to be the major factor in methomyl degradation in soil(4). The half-life of methomyl in three greenhouse soils was about 3-14 days(5). The half-life of methomyl was reported as 30 days in soil(6).
Bioaccumulative potential
An estimated BCF of 3 was calculated for methomyl(SRC), using a log Kow of 0.6(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).
Mobility in soil
The measured Koc of methomyl was reported as 160(1). According to a classification scheme(2), this Koc value suggests that methomyl is expected to have moderate mobility in soil. Under field conditions and using laboratory studies, only slight movement of methomyl has been observed in soil(3,4).
Other adverse effects
no data available
SECTION 13: Disposal considerations
Disposal methods
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
UN Number
ADR/RID: UN2991 (For reference only, please check.)
IMDG: UN2991 (For reference only, please check.)
IATA: UN2991 (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: CARBAMATE PESTICIDE, LIQUID, TOXIC, FLAMMABLE, flash point not less than 23 °C (For reference only, please check.)
IMDG: CARBAMATE PESTICIDE, LIQUID, TOXIC, FLAMMABLE, flash point not less than 23 °C (For reference only, please check.)
IATA: CARBAMATE PESTICIDE, LIQUID, TOXIC, FLAMMABLE, flash point not less than 23 °C (For reference only, please check.)
Transport hazard class(es)
ADR/RID: 6.1 (For reference only, please check.)
IMDG: 6.1 (For reference only, please check.)
IATA: 6.1 (For reference only, please check.)
Packing group, if applicable
ADR/RID: I (For reference only, please check.)
IMDG: I (For reference only, please check.)
IATA: I (For reference only, please check.)
Environmental hazards
ADR/RID: Yes
IMDG: Yes
IATA: Yes
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
Safety, health and environmental regulations specific for the product in question
SECTION 16: Other information
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Other Information
Methomyl is a mixture of (Z)- and (E)-isomers.If the pesticide is present in a formulation containing hydrocarbon solvents, vomiting should not be induced.Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.If the substance is formulated with solvents also consult the ICSCs of these materials.Carrier solvents used in commercial formulations may change physical and toxicological properties.Do NOT take working clothes home.Depending on the degree of exposure, periodic medical examination is suggested.