Methidathion SDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
- Product name： Methidathion
- CAS： 950-37-8
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses： For R&D use only. Not for medicinal, household or other use.
- Uses advised against： none
Company Identification
- Company：Chemicalbook.in
- Address：5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
- Telephone：+91 9550333722
SECTION 2: Hazards identification
Classification of the substance or mixture
Acute toxicity - Category 2, Oral
Acute toxicity - Category 4, Dermal
Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1
GHS label elements, including precautionary statements
-
Pictogram(s)
- Signal word Danger
H300 Fatal if swallowed
H312 Harmful in contact with skin
H410 Very toxic to aquatic life with long lasting effects
P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P273 Avoid release to the environment.
P301+P316 IF SWALLOWED: Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P317 Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P391 Collect spillage.
P405 Store locked up.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
Substance
- Chemical name: Methidathion
- Common names and synonyms: Methidathion
- CAS number: 950-37-8
- EC number: 213-449-4
- Concentration: 100%
SECTION 4: First aid measures
Description of necessary first-aid measures
Fresh air, rest. Artificial respiration may be needed. Refer immediately for medical attention.
Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer immediately for medical attention. Wear protective gloves when administering first aid.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Rinse mouth. Give a slurry of activated charcoal in water to drink. Refer immediately for medical attention.
Most important symptoms/effects, acute and delayed
This material is poisonous to humans. Its toxic effects are by action on the nervous system. Human volunteers ingesting 0.11 mg/kg/day for 6 weeks had no clinical effects. (EPA, 1998)
Indication of immediate medical attention and special treatment needed, if necessary
Airway protection. Insure that a clear airway exists. Intubate the patients and aspirate the secretions with a large-bore suction device if necessary. Administer oxygen by mechanically assisted pulmonary ventilation if respiration is depressed. Improve tissue oxygenation as much as possible before administering atropine, so as to minimize the risk of ventricular fibrillation. In severe poisonings, it may be necessary to support pulmonary ventilation mechanically for several days. Organophosphate pesticides
SECTION 5: Firefighting measures
Suitable extinguishing media
Self contained breathing apparatus with a full facepiece operated in pressure demand, or other positive pressure mode /should be used in firefighting/. Parathion
Specific hazards arising from the chemical
Non-Specific -- Organophosphorus Pesticide, n.o.s.) Container may explode in heat of fire. Fire and runoff from fire control water may produce irritating or poisonous gases. Stable in neutral or weak acid solution. Hydrolyzed by alkali. (EPA, 1998)
Special protective actions for fire-fighters
Use water spray. Use dry powder. Use carbon dioxide.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Personal protection: complete protective clothing including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Sweep spilled substance into covered sealable containers. Carefully collect remainder. Then store and dispose of according to local regulations.
Environmental precautions
Personal protection: complete protective clothing including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Sweep spilled substance into covered sealable containers. Carefully collect remainder. Then store and dispose of according to local regulations.
Methods and materials for containment and cleaning up
Ventilate area of spill or leak. collect for reclamation, or absorb in vermiculite, dry sand, earth, or a similar material. parathion
SECTION 7: Handling and storage
Precautions for safe handling
NO open flames. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs. Well closed. Store in an area without drain or sewer access.Store in dry, well-ventilated, secure area out of reach of children and animals.
SECTION 8: Exposure controls/personal protection
Control parameters
no data available
no data available
Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures, such as personal protective equipment (PPE)
Wear face shield or eye protection in combination with breathing protection.
Protective gloves. Protective clothing.
Use local exhaust or breathing protection.
no data available
SECTION 9: Physical and chemical properties and safety characteristics
-
Physical state：
Methidathion is a colorless crystals. This material is used as a non-systemic insecticide. (EPA, 1998)
-
Colour：
Colorless crystals
-
Odour：
Organophosphate odor
-
Melting point/freezing point：
39-40°C
-
Boiling point or initial boiling point and boiling range：
347.7°C at 760 mmHg
-
Flammability：
Combustible. Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire.
-
Lower and upper explosion limit/flammability limit：
no data available
-
Flash point：
164.1°C
-
Auto-ignition temperature：
no data available
-
Decomposition temperature：
no data available
-
pH：
no data available
-
Kinematic viscosity：
no data available
-
Solubility：
Solubility (all in g/L at 20 deg C): ethanol (150); acetone (670); toluene (720); hexane (11); n-octanol (14)
-
Partition coefficient n-octanol/water：
log Kow = 2.20
-
Vapour pressure：
1e-06 mm Hg at 68° F (EPA, 1998)
-
Density and/or relative density：
1.6 g/cm3
-
Relative vapour density：
no data available
-
Particle characteristics：
no data available
SECTION 10: Stability and reactivity
Reactivity
Decomposes on heating. This produces toxic fumes.
Chemical stability
Relatively stable to hydrolysis in neutral, or slightly acidic media, less stable in more acidic (pH 1), or in alkaline media (pH 13, 50% loss in 30 min @ 25 deg C).
Possibility of hazardous reactions
Organophosphates, such as METHIDATHION, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.
Conditions to avoid
no data available
Incompatible materials
no data available
Hazardous decomposition products
When heated to decomposition it emits very toxic fumes of /oxides of nitrogen, oxides of phosphorous and oxides of sulfur/.
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 Guinea pig oral 25 mg/kg
- Inhalation: LC50 Rat inhalation 3.6 mg/L (4 hr) Technical
- Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
Cancer Classification: Group C Possible Human Carcinogen
Reproductive toxicity
no data available
STOT-single exposure
Cholinesterase inhibition. The substance may cause effects on the nervous system. This may result in convulsions and respiratory depression. Exposure could cause death. The effects may be delayed. Medical observation is indicated.
STOT-repeated exposure
Cholinesterase inhibition. Cumulative effects are possible. See Acute Hazards/Symptoms.
Aspiration hazard
A harmful concentration of airborne particles can be reached quickly when dispersed.
SECTION 12: Ecological information
Toxicity
- Toxicity to fish: LC50; Species: Lepomis macrochirus (Bluegill); Conditions: freshwater, static; Concentration: 2.2 ug/L for 96 hr (95% confidence interval: 0.9-5.1 ug/L) /95% purity
- Toxicity to daphnia and other aquatic invertebrates: EC50; Species: Daphnia magna (Water Flea) 1st instar larvae; Conditions: freshwater, static; Concentration: 6.4 ug/L for 48 hr (95% confidence interval: 5.1-8.1 ug/L); Effect: intoxication, immobilization
- Toxicity to algae: EC50; Species: Anabaena flosaquae (Blue-Green Algae); Conditions: freshwater, static, 24 deg C; Concentration: 67521 ug/L for 96 hr; Effect: decreased population biomass /96.1% purity technical product
- Toxicity to microorganisms: no data available
Persistence and degradability
AEROBIC: A half-life in aerobic soil of 11 days has been reported(1). Methidathion, at a concentration of 4 mg, containing chain labeled C14 was added to 400 cu cm of 4 different soils and incubated at 25 deg C(2). After 16 weeks, 7% C14, 8% C14, 1% C14, and 2% C14 remained in Puyallop sandy loam, Sultan silt loam, Chehalis clay loam, and organic soil, respectively(2). After 16 weeks, 49-60% methidathion remained in fumigated controls with <3% of the radioactivity was expired as CO2(2). An avg half-life of 12.42 days was measured for 1-50 ug/L methidathion added to filtered water collected during May-April, 1997 from the Limon River, between Mara and Paez, State of Zula, Argentina(3).
Bioaccumulative potential
Whole-body BCFs of 3.0, 2.2, 1.5, and 2.6 were measured using carp (Cyprino carpio L.) after 24, 72, 120, and 196 hr exposure to 2.6 ug/L methidathion, respectively(1). Average BCFs after 168 hr exposures were 6.4, 5.6, 4.6, 3.6, and 5.5 for guppy (female) (Lebistes reticulatus), guppy (male), killifish (Oryzias latipes), goldfish (Carassius aurapus), and cloud mountain fish (Tanichthys albonubes), respectively(2). According to a classification scheme(3), these BCF values suggest bioconcentration in aquatic organisms is low(SRC). Tests using the Mediterranean mussel, Mytillus galloprovincialis, resulted in a BCF value of 193(4).
Mobility in soil
Experimental Koc values of 34(1) and 761(2) in soil have been reported. According to a classification scheme(3), these Koc values suggest that methidathion is expected to have very high to low mobility in soil(SRC). Experimental Koc values of 7 and 56 were determined in 2 different pond sediments at pH 5.9 and 6.5, respectively(4). Methidathion was shown to have no to moderate leaching potential using agricultural soils characterized by high organic content from the Canary Island of Tenerife(5).
Other adverse effects
no data available
SECTION 13: Disposal considerations
Disposal methods
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
UN Number
ADR/RID: UN2783 (For reference only, please check.)
IMDG: UN2783 (For reference only, please check.)
IATA: UN2783 (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: ORGANOPHOSPHORUS PESTICIDE, SOLID, TOXIC (For reference only, please check.)
IMDG: ORGANOPHOSPHORUS PESTICIDE, SOLID, TOXIC (For reference only, please check.)
IATA: ORGANOPHOSPHORUS PESTICIDE, SOLID, TOXIC (For reference only, please check.)
Transport hazard class(es)
ADR/RID: 6.1 (For reference only, please check.)
IMDG: 6.1 (For reference only, please check.)
IATA: 6.1 (For reference only, please check.)
Packing group, if applicable
ADR/RID: I (For reference only, please check.)
IMDG: I (For reference only, please check.)
IATA: I (For reference only, please check.)
Environmental hazards
ADR/RID: Yes
IMDG: Yes
IATA: Yes
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
Safety, health and environmental regulations specific for the product in question
SECTION 16: Other information
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Other Information
Carrier solvents used in commercial formulations may change physical and toxicological properties.Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.Do NOT take working clothes home.