Dodecachloropentacyclo[5.2.1.02,6.03,9.05,8]decane SDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
- Product name： Dodecachloropentacyclo[5.2.1.02,6.03,9.05,8]decane
- CAS： 2385-85-5
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses： For R&D use only. Not for medicinal, household or other use.
- Uses advised against： none
Company Identification
- Company：Chemicalbook.in
- Address：5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
- Telephone：+91 9550333722
SECTION 2: Hazards identification
Classification of the substance or mixture
Acute toxicity - Category 4, Oral
Acute toxicity - Category 4, Dermal
Carcinogenicity, Category 2
Reproductive toxicity, Additional category for effects on or via lactation
Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1
Reproductive toxicity, Category 2
GHS label elements, including precautionary statements
-
Pictogram(s)
- Signal word Warning
H302 Harmful if swallowed
H312 Harmful in contact with skin
H351 Suspected of causing cancer
H362 May cause harm to breast-fed children
H410 Very toxic to aquatic life with long lasting effects
P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P203 Obtain, read and follow all safety instructions before use.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P263 Avoid contact during pregnancy and while nursing.
P273 Avoid release to the environment.
P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P317 Get medical help.
P321 Specific treatment (see ... on this label).
P362+P364 Take off contaminated clothing and wash it before reuse.
P318 IF exposed or concerned, get medical advice.
P391 Collect spillage.
P405 Store locked up.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
Substance
- Chemical name: Dodecachloropentacyclo[5.2.1.02,6.03,9.05,8]decane
- Common names and synonyms: Dodecachloropentacyclo[5.2.1.02,6.03,9.05,8]decane
- CAS number: 2385-85-5
- EC number: 219-196-6
- Concentration: 100%
SECTION 4: First aid measures
Description of necessary first-aid measures
Move the victim into fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration and consult a doctor immediately. Do not use mouth to mouth resuscitation if the victim ingested or inhaled the chemical.
Take off contaminated clothing immediately. Wash off with soap and plenty of water. Consult a doctor.
Rinse with pure water for at least 15 minutes. Consult a doctor.
Rinse mouth with water. Do not induce vomiting. Never give anything by mouth to an unconscious person. Call a doctor or Poison Control Center immediately.
Most important symptoms/effects, acute and delayed
INGESTION, INHALATION, OR SKIN EXPOSURE: Gas- trointestinal irritation with nausea, vomiting, and possible diarrhea. Malaise, headache, CNS excitation with tremor, paresthesias, ataxia, confusion, convulsions, and ventricular fibrillation. CNS depression and central respiratory paralysis may occur. (USCG, 1999)
Indication of immediate medical attention and special treatment needed, if necessary
Basic treatment: Establish a patent airway (oropharyngeal or nasopharyngeal airway, if needed). Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary . Anticipate seizures and treat if necessary . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with 0.9% saline (NS) during transport . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool. Administer activated charcoal . Lindane and related compounds
SECTION 5: Firefighting measures
Suitable extinguishing media
Liquid products containing organic solvents may be flammable. Extinguish fires with alcohol-resistant foam, carbon dioxide, or powder. With sufficient burning or external heat, mirex will decompose, emitting toxic fumes. Fire-fighters should wear a self-contained breathing apparatus, eye protection, and full protective clothing.
Specific hazards arising from the chemical
Behavior in Fire: Supports combustion (USCG, 1999)
Special protective actions for fire-fighters
Wear self-contained breathing apparatus for firefighting if necessary.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Avoid dust formation. Avoid breathing mist, gas or vapours.Avoid contacting with skin and eye. Use personal protective equipment.Wear chemical impermeable gloves. Ensure adequate ventilation.Remove all sources of ignition. Evacuate personnel to safe areas.Keep people away from and upwind of spill/leak.
Environmental precautions
Prevent further spillage or leakage if it is safe to do so. Do not let the chemical enter drains. Discharge into the environment must be avoided.
Methods and materials for containment and cleaning up
Before dealing with any spillage, precautions should be taken as required and appropriate personal protection should be used. Prevent liquid from spreading or contaminating other cargo and vegetation, and avoid pollution of surface waters and ground water by using the most suitable available material, e.g., earth or sand. Absorb spilled liquid with sawdust, sand, or earth, sweep up and place it in a closeable container for later transfer to a safe place for disposal. As soon as possible after the spillage and before re-use, cover all contaminated areas with damp sawdust, sand, or earth. Sweep up and place in a closeable container for later transfer to a safe place for disposal. Care should be taken to avoid run-off into surface waters or drains.
SECTION 7: Handling and storage
Precautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Products should be stored in locked buildings, preferably dedicated to insecticides. Keep products out of reach of children and unauthorized personnel. Do not store near foodstuffs or animal feed.
SECTION 8: Exposure controls/personal protection
Control parameters
| Component | Dodecachloropentacyclo[5.2.1.02,6.03,9.05,8]decane | |||
|---|---|---|---|---|
| CAS No. | 2385-85-5 | |||
| Limit value - Eight hours | Limit value - Short term | |||
| ppm | mg/m3 | ppm | mg/m3 | |
| Hungary | ? | POP | ? | ? |
| Remarks | ||||
| Hungary | POP = Persistent Organic Pollutant | |||
no data available
Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures, such as personal protective equipment (PPE)
Wear tightly fitting safety goggles with side-shields conforming to EN 166(EU) or NIOSH (US).
Wear fire/flame resistant and impervious clothing. Handle with gloves. Gloves must be inspected prior to use. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.
If the exposure limits are exceeded, irritation or other symptoms are experienced, use a full-face respirator.
no data available
SECTION 9: Physical and chemical properties and safety characteristics
-
Physical state：
Mirex is an odorless white crystalline solid. (USCG, 1999)
-
Colour：
Snow-white crystals from benzene
-
Odour：
Odorless
-
Melting point/freezing point：
905° F (decomposes) (NTP, 1992)
-
Boiling point or initial boiling point and boiling range：
421.1°C at 760mmHg
-
Flammability：
no data available
-
Lower and upper explosion limit/flammability limit：
no data available
-
Flash point：
201.9°C
-
Auto-ignition temperature：
no data available
-
Decomposition temperature：
no data available
-
pH：
no data available
-
Kinematic viscosity：
no data available
-
Solubility：
less than 1 mg/mL at 75° F (NTP, 1992)
-
Partition coefficient n-octanol/water：
log Kow = 6.89
-
Vapour pressure：
6.55E-07mmHg at 25°C
-
Density and/or relative density：
2.25g/cm3
-
Relative vapour density：
18.8 (NTP, 1992) (Relative to Air)
-
Particle characteristics：
no data available
SECTION 10: Stability and reactivity
Reactivity
no data available
Chemical stability
Very stable at normal temperatures.
Possibility of hazardous reactions
Supports combustionMIREX is sensitive to exposure to sunlight. This compound may react with strong oxidizers. It reacts with lithium and tertiary butyl alcohol. (NTP, 1992)
Conditions to avoid
no data available
Incompatible materials
no data available
Hazardous decomposition products
Decomposes above 500 deg C to give hexachlorobenzene; hexachloropentadiene was found in small amounts in the thermal residue; the products identified from vapor phase were carbon monoxide, carbon dioxide, hydrogen chloride, chlorine, carbon tetrachloride, & phosgene.
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 Rat male oral 306 mg/kg
- Inhalation: no data available
- Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
Classification of carcinogenicity: 1) evidence in humans: no data; 2) evidence in animals: sufficient. Overall summary evaluation of carcinogenic risk to humans is Group 2B: The agent is possibly carcinogenic to humans. From table
Reproductive toxicity
no data available
STOT-single exposure
no data available
STOT-repeated exposure
no data available
Aspiration hazard
no data available
SECTION 12: Ecological information
Toxicity
- Toxicity to fish: LC50 Pimephales promelas (fathead minnow), greater than 100 mg/l/96 hr at 18 deg C, wt 1.3 g /wettable powder, 50%; static bioassay without aeration
- Toxicity to daphnia and other aquatic invertebrates: EC50 Daphnia magna (daphnid), >1.0 mg/L/48 hr at 17 deg C, 1st instar; Effect: intoxication, immobilization /technical material, 98%; static bioassay without aeration
- Toxicity to algae: no data available
- Toxicity to microorganisms: no data available
Persistence and degradability
AEROBIC: Following the application of 0.5 grams mirex to 100 grams of soil (nine different soils), followed by addition of distilled water to bring the soil moisture to the field capacity, 88-99% of the initially applied amount of mirex was recovered following a 3 month incubation period, and 93-99% was recovered in the soils 6 months post application(1). Generally mirex is resistant to attack by bacteria and fungi, and can inhibit the growth of actinomyctes(1). Although mirex is taken up by micro-organisms(1), plants(2,4) and higher animals including fish(5) and rats(2), it is not metabolized(2). Analysis of soils from spill sites 5 and 12 years after the accidents, suggests that dechlorination takes place very slowly and kepone is a biotransformation product of mirex(3). Twelve years after the application of mirex to soil at one pound per acre, 50% of the mirex and mirex-related organochlorine compounds remained in the soil; 65-73% of the residues consisted of mirex and 3-6% consisted of chlordecone(3). Although concentrations were slightly higher, similar ratios of mirex (76-81%) and chlordecone (l-6%) residues were seen five years after an accidental spill of mirex bait on soil. Kepone was also identified as a transformation product of mirex in estuaries(4). Neither C(14) labeled mirex or kepone degraded in aerobic hydrosoils from the Little Dixie Reservoir and James River tributary, Richmond VA(5).
Bioaccumulative potential
There is evidence for degradation of mirex to chlordecone (kepone) in the environment. both mirex & kepone are highly persistent & have high lipid:water partition coefficients & have been shown to bioconcentrate several thousandfold in food chains.
Mobility in soil
The average Koc value for mirex in 4 samples of sediment obtained from Coyote Creek, CA was 2.4X10+7(1). The Koc value of mirex in an unspecified soil was 5800(2). According to a classification scheme(3), this average Koc value suggests that mirex is expected to be immobile in soil(SRC).
Other adverse effects
no data available
SECTION 13: Disposal considerations
Disposal methods
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
UN Number
ADR/RID: UN2762 (For reference only, please check.)
IMDG: UN2762 (For reference only, please check.)
IATA: UN2762 (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: ORGANOCHLORINE PESTICIDE, LIQUID, FLAMMABLE, TOXIC, flash point less than 23 °C (For reference only, please check.)
IMDG: ORGANOCHLORINE PESTICIDE, LIQUID, FLAMMABLE, TOXIC, flash point less than 23 °C (For reference only, please check.)
IATA: ORGANOCHLORINE PESTICIDE, LIQUID, FLAMMABLE, TOXIC, flash point less than 23 °C (For reference only, please check.)
Transport hazard class(es)
ADR/RID: 3 (For reference only, please check.)
IMDG: 3 (For reference only, please check.)
IATA: 3 (For reference only, please check.)
Packing group, if applicable
ADR/RID: I (For reference only, please check.)
IMDG: I (For reference only, please check.)
IATA: I (For reference only, please check.)
Environmental hazards
ADR/RID: Yes
IMDG: Yes
IATA: Yes
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
Safety, health and environmental regulations specific for the product in question
SECTION 16: Other information
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/