Methylarsonic acid SDS
SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifier
- Product name： Methylarsonic acid
- CAS： 124-58-3
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses： For R&D use only. Not for medicinal, household or other use.
- Uses advised against： none
Company Identification
- Company：Chemicalbook.in
- Address：5 vasavi Layout Basaveswara Nilayam Pragathi Nagar Hyderabad, India -500090
- Telephone：+91 9550333722
SECTION 2: Hazards identification
Classification of the substance or mixture
Acute toxicity - Category 3, Oral
Acute toxicity - Category 3, Inhalation
Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1
GHS label elements, including precautionary statements
-
Pictogram(s)
- Signal word Danger
H301 Toxic if swallowed
H331 Toxic if inhaled
H410 Very toxic to aquatic life with long lasting effects
P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P273 Avoid release to the environment.
P301+P316 IF SWALLOWED: Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P330 Rinse mouth.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P316 Get emergency medical help immediately.
P391 Collect spillage.
P405 Store locked up.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
SECTION 3: Composition/information on ingredients
Substance
- Chemical name: Methylarsonic acid
- Common names and synonyms: Methylarsonic acid
- CAS number: 124-58-3
- EC number: 204-705-6
- Concentration: 100%
SECTION 4: First aid measures
Description of necessary first-aid measures
Fresh air, rest. Refer for medical attention.
Remove contaminated clothes. Rinse and then wash skin with water and soap.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Rinse mouth. Refer for medical attention .
Most important symptoms/effects, acute and delayed
no data available
Indication of immediate medical attention and special treatment needed, if necessary
Dairy cows /were fed/ cottonseed ration containing maa. the maa had no effect on cows, with very little residue accumulating in tissues or milk. the maa appeared to be poorly absorbed from intestinal tract & was rapidly excreted in urine.
SECTION 5: Firefighting measures
Suitable extinguishing media
In case of fire in the surroundings, use appropriate extinguishing media.
Specific hazards arising from the chemical
Not combustible. Gives off irritating or toxic fumes (or gases) in a fire.
Special protective actions for fire-fighters
In case of fire in the surroundings, use appropriate extinguishing media.
SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.
Environmental precautions
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.
Methods and materials for containment and cleaning up
Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.
SECTION 7: Handling and storage
Precautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Separated from strong bases and food and feedstuffs. Dry. Store in an area without drain or sewer access.SOLID FORMULATIONS ARE SOMEWHAT HYGROSCOPIC & SHOULD BE STORED IN DRY PLACE.
SECTION 8: Exposure controls/personal protection
Control parameters
no data available
no data available
Appropriate engineering controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures, such as personal protective equipment (PPE)
Wear safety goggles or eye protection in combination with breathing protection if powder.
Protective gloves.
Use local exhaust or breathing protection.
no data available
SECTION 9: Physical and chemical properties and safety characteristics
-
Physical state：
Solid
-
Colour：
Monoclinic, spear-shaped plates from absolute alcohol
-
Odour：
no data available
-
Melting point/freezing point：
161°C
-
Boiling point or initial boiling point and boiling range：
393.3°C at 760mmHg
-
Flammability：
Not combustible. Gives off irritating or toxic fumes (or gases) in a fire.
-
Lower and upper explosion limit/flammability limit：
no data available
-
Flash point：
205.8°C
-
Auto-ignition temperature：
no data available
-
Decomposition temperature：
no data available
-
pH：
no data available
-
Kinematic viscosity：
no data available
-
Solubility：
Soluble in ethanol
-
Partition coefficient n-octanol/water：
no data available
-
Vapour pressure：
<7.5X10-8 mm Hg @ 25 deg C
-
Density and/or relative density：
no data available
-
Relative vapour density：
no data available
-
Particle characteristics：
no data available
SECTION 10: Stability and reactivity
Reactivity
Decomposes on heating. This produces toxic fumes of arsenic oxides (see ICSC 0378). The solution in water is a medium strong acid.
Chemical stability
STABLE
Possibility of hazardous reactions
Decomposes on heating. This produces toxic fumes of arsenic oxides (see ICSC 0378). The solution in water is a medium strong acid.
Conditions to avoid
no data available
Incompatible materials
no data available
Hazardous decomposition products
When heated to decomposition it emits toxic fumes of /arsenic/.
SECTION 11: Toxicological information
Acute toxicity
- Oral: LD50 Rat oral 961 mg/kg
- Inhalation: no data available
- Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
no data available
Reproductive toxicity
no data available
STOT-single exposure
The substance is mildly irritating to the eyes, skin and respiratory tract. Ingestion could cause gastroenteritis. Medical observation is indicated.
STOT-repeated exposure
The substance may have effects on the kidneys and liver. This may result in impaired functions. This substance is carcinogenic to humans.
Aspiration hazard
A harmful concentration of airborne particles can be reached quickly when dispersed.
SECTION 12: Ecological information
Toxicity
- Toxicity to fish: no data available
- Toxicity to daphnia and other aquatic invertebrates: no data available
- Toxicity to algae: no data available
- Toxicity to microorganisms: no data available
Persistence and degradability
The metabolism of maa to inorganic arsenic is the main mechanism of herbicide degradation... the assoc of herbicidal breakdown with the general microbiological activity suggests that the oxidation of maa /methanearsonic acid/ occurred coincidentally with the metab of soil org matter. on the other hand, both norfolk loamy sand samples (with & without organic matter added) showed an increased dsma /disodium salt of maa/ decomposition relative to soil organic matter. this suggested an adaptation of the microbial population to metabolize the methyl carbon of maa. /investigators/...exam the degradation of msma /monosodium salt of maa/ on 4 soils. they concluded that soil microorganisms appeared to play some role in the decomposition process. a fungus, several actinomycetes, & several bacteria were isolated using soil enrichment techniques. the organisms degraded 3, 13 or 9, & 20% of the msma in 11 days, respectively. however, in the absence of an energy source, microbial metabolism of the organic arsenical was nonexistent. the products of metabolism were carbon dioxide & arsenate. no arsenite could be detected.
Bioaccumulative potential
In aquatic model ecosystem testing bioaccumulation & distribution of (14)c-methanearsonic acid, bioaccumulation ratios for daphnids, gambusia, algae & crayfish were 5, 127, 34, & 5, respectively. bioaccumulation ratio values declined for crayfish & catfish when removed from (14)c-methanearsonic acid exposure to untreated water. (14)c was found @ higher % rate in residue of exptl organisms than (74)as-arsenate.
Mobility in soil
no data available
Other adverse effects
no data available
SECTION 13: Disposal considerations
Disposal methods
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
SECTION 14: Transport information
UN Number
ADR/RID: UN2759 (For reference only, please check.)
IMDG: UN2759 (For reference only, please check.)
IATA: UN2759 (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: ARSENICAL PESTICIDE, SOLID, TOXIC (For reference only, please check.)
IMDG: ARSENICAL PESTICIDE, SOLID, TOXIC (For reference only, please check.)
IATA: ARSENICAL PESTICIDE, SOLID, TOXIC (For reference only, please check.)
Transport hazard class(es)
ADR/RID: 6.1 (For reference only, please check.)
IMDG: 6.1 (For reference only, please check.)
IATA: 6.1 (For reference only, please check.)
Packing group, if applicable
ADR/RID: I (For reference only, please check.)
IMDG: I (For reference only, please check.)
IATA: I (For reference only, please check.)
Environmental hazards
ADR/RID: Yes
IMDG: Yes
IATA: Yes
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
SECTION 15: Regulatory information
Safety, health and environmental regulations specific for the product in question
SECTION 16: Other information
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
Other Information
Do NOT take working clothes home.Depending on the degree of exposure, periodic medical examination is suggested.The recommendations on this card also apply to monosodium methanarsonate and disodium methanarsonate.